| | 53994-73-3 Basic information More.. |
| Product Name: | Cefaclor | | Synonyms: | CEFACLOR;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(aminophenylacetyl)amino]-3-chloro-8-oxo-, [6R-[6α,7β(R*)]]-;Alfacet;Kefral;S 6472;Cefaclor (Ceclor);(6R,7R)-7-{[(2R)-2-AMINO-2-PHENYLACETYL]AMINO}-3-CHLORO-8-OXO-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLIC ACID;Cefachlor | | CAS: | 53994-73-3 | | MF: | C15H14ClN3O4S | | MW: | 367.81 | | EINECS: | 258-909-5 | | Mol File: | 53994-73-3.mol |  |
Use
Cefaclor (Ceclor) is an orally active semisyntheticcephalosporin that was introduced in the American market in1979. It differs structurally from cephalexin in that the 3-methyl group has been replaced by a chlorine atom. It issynthesized from the corresponding 3-methylenecepham sulfoxideester by ozonolysis, followed by halogenation of theresulting β-ketoester. The 3-methylenecepham sulfoxideesters are prepared by rearrangement of the corresponding 6-acylaminopenicillanic acid derivative. Cefaclor is moderatelystable in acid and achieves enough oral absorption to provideeffective plasma levels (equal to about two-thirds of thoseobtained with cephalexin). The compound is apparentlyunstable in solution, since about 50% of its antimicrobial activityis lost in 2 hours in serum at 37°C. The antibacterialspectrum of activity is similar to that of cephalexin, but it isclaimed to be more potent against some species sensitiveto both agents. Currently, the drug is recommended for thetreatment of non–life-threatening infections caused by H.influenzae, particularly strains resistant to ampicillin.
- Cefaclor
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- US $0.00 / Kg/Drum
- 2024-08-26
- CAS:53994-73-3
- Min. Order: 1KG
- Purity: 95%-101%;USP
- Supply Ability: 500KGS
- Cefaclor
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- US $0.00-0.00 / kg
- 2024-08-22
- CAS:53994-73-3
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- Cefaclor
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- US $0.00 / Kg
- 2024-04-09
- CAS:53994-73-3
- Min. Order: 1Kg
- Purity: 99%
- Supply Ability: 10kg
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53994-73-3
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