82034-46-6 Basic information More..
Product Name:Loteprednol etabonate
Synonyms:LOTEPREDNOL ETABONATE;Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, chloromethyl ester, (11b,17a)-;Lotemax;17α-(Ethoxycarbonyloxy)-11β-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid chloromethyl ester;17α-(Ethoxycarbonyloxy)-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic acid chloromethyl ester;3-Oxo-11β-hydroxy-17α-(ethoxycarbonyloxy)androsta-1,4-diene-17-carboxylic acid chloromethyl ester;Lotoprednol etabonate;CDDD-5604, HGP-1, P-5604, Alrex, Lotemax
CAS:82034-46-6
MF:C24H31ClO7
MW:466.95
EINECS:200-010-0
Mol File:82034-46-6.mol
82034-46-6

Use

Loteprednol (as Loteprednol Etabonate) is a topical anti-inflammatory corticosteroid. Loteprednol etabonate (LE) has a 17-chloromethyl ester, in lieu of a ketone group, and a 17-etabonate group. LE is highly lipophilic and binds with high affinity to the glucocorticoid receptor. Any unbound LE is metabolized to inactive metabolites. Loteprednol etabonate is used in ophthalmic solution for the treatment of steroid responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, uveitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and selected infective conjunctivitis. It is used in ophthalmic ointment for the treatment of post-operative inflammation and pain following ocular surgery. As a nasal spray, it is used for the treatment and management of seasonal allergic rhinitis.

Loteprednol etabonate manufacturers

  • Loteprednol Etabonate
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:82034-46-6
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • Loteprednol etabonate
  • US $100.00 / KG
  • 2021-05-11
  • CAS:82034-46-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 1000t
  • Loteprednol etabonate
  • US $150.00 / KG
  • 2020-09-02
  • CAS:82034-46-6
  • Min. Order: 1KG
  • Purity: 99.9%
  • Supply Ability: 10tons
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