80890-47-7 Basic information More..
Product Name:CONCANAMYCIN A
Synonyms:CONCANAMYCIN A;CONCANAMYCIN A, STREPTOMYCES SP;concanamycin A from streptomyces species;A661-I;Antibiotic A661I;Antibiotic S-45A;S-45A;(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-3,17-dimethoxy-5,7,11,13-tetramethyloxacyclooctadeca-3,5,13,15-tetraen-2-one
CAS:80890-47-7
MF:C46H75NO14
MW:866.09
EINECS:620-709-4
Mol File:80890-47-7.mol
80890-47-7

Use

Concanamycin A is the major analogue of the concanamycin complex produced by Streptomyces sp.. It has been shown to act as a potent and specific vacuolar-ATPase inhibitor. Concanamycin A inhibits the acidification of organelles and blocks cell surface expression of viral envelope glycoproteins without affecting their synthesis. It also interferes with intracellular protein trafficking and inhibits perforin- and Fas-based lytic pathways in cell-mediated cytotoxicity. Concanamycins are structurally related to the bafilomycins.

CONCANAMYCIN A manufacturers

  • Concanamycin A
  • US $273.00 / μg
  • 2024-11-01
  • CAS:80890-47-7
  • Min. Order:
  • Purity:
  • Supply Ability: 10g
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