307983-31-9(GRA Ex-25)

307983-31-9 Basic information More..
Product Name:GRA Ex-25
Synonyms:GRA Ex-25;B-Alanine, N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-;β-Alanine, N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-;GRA Ex-25 USP/EP/BP;GRA Ex-25[GRA-Ex-25;GCGR,inhibit,GRA Ex 25,Inhibitor,GRA Ex-25,Glucagon Receptor,GRA Ex25;3-(4-((1-(trans-4-(tert-Butyl)cyclohexyl)-3-(4-(trifluoromethoxy)phenyl)ureido)methyl)benzamido)propanoic acid
CAS:307983-31-9
MF:C29H36F3N3O5
MW:563.61
EINECS:
Mol File:Mol File
307983-31-9
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Remarks:GRA Ex-25 is an orally active human glucagon receptor antagonist in a transgenic murine pharmacodynamic model, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. GCGR has ev
CB Index: 65
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