871307-18-5(4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile)

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Product Name:4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile
Synonyms:4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile;Tpl2 Kinase Inhibitor;4-[(3-Chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-1,7-naphthyridine-3-carbonitrile;Tpl2-IN-2p;TC-S 7006;1,7-Naphthyridine-3-carbonitrile, 4-[(3-chloro-4-fluorophenyl)amino]-6-[(3-pyridinylmethyl)amino]-;Tpl2 Kinase Inhibitor 1;Tpl2 Kinase Inhibitor 1,Tpl-2 Kinase Inhibitor 1
CAS:871307-18-5
MF:C21H14ClFN6
MW:404.83
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Mol File:Mol File
871307-18-5
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CAS:871307-18-5
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Purity:≥99% by HPLC Remarks:TC-S 7006 is a potent, selective and reversible Tpl2 (Cot; MAP3K8) inhibitor (IC50 = 50 nM) with selectivity for Tpl2 over MEK, p38, Src, MK2, PKC and EGFR. TC-S 7006 was shown to inhibit LPS-induced
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