Resolvin D5 manufacturers
|
| Resolvin D5 Basic information |
Product Name: | Resolvin D5 | Synonyms: | (5Z,7S,8E,10Z,13Z,15E,17S,19Z)-7,17-dihydroxydocosa-5,8,10,13,15,19-hexaenoic acid;Resolvin D5;7(S),17(S)-Resolvin D5;4,8,10,13,15,19-Docosahexaenoic acid, 7,17-dihydroxy-, (4Z,7S,8E,10Z,13Z,15E,17S,19Z)- | CAS: | 578008-43-2 | MF: | C22H32O4 | MW: | 360.49 | EINECS: | | Product Categories: | | Mol File: | 578008-43-2.mol | ![Resolvin D5 Structure](CAS/20181012/GIF/578008-43-2.gif) |
| Resolvin D5 Chemical Properties |
Boiling point | 559.4±50.0 °C(Predicted) | density | 1.048±0.06 g/cm3(Predicted) | storage temp. | Store at -80°C,protect from light | solubility | DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml | pka | 4.58±0.10(Predicted) |
| Resolvin D5 Usage And Synthesis |
Description | Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA; ) and docosahexaenoic acid (DHA; ). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D5 (RvD5) is a DHA-derived resolvin generated by a double dioxygenation mechanism. RvD5 has been identified in media from ionophore-stimulated trout brain cells, in human synovial fluid from patients with rheumatoid arthritis, and in exudates of bacterial infections in mice. RvD5 stimulates the phagocytosis of E. coli by human macrophages, and RvD5 methyl ester enhances bacterial killing in mice inoculated with E. coli. Analytical and biological comparisons of synthetic RvD5 with endogenously derived RvD5 have confirmed its identity as matching the natural product. | Uses | 7(S),17(S)-Resolvin D5 is a docosahexaenoic acid (D494500), which is a ω-3 fatty acid that is found in the brain, synapses, and retina. It also exhibits anti-inflammatory activity. |
| Resolvin D5 Preparation Products And Raw materials |
|