| Company Name: |
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| Tel: |
4008-099-669 |
| Email: |
23419001name@qq.com |
| Products Intro: |
Cas:1009104-85-1
ProductName:SMAD3 Inhibitor, SIS3
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| Company Name: |
Cayman Chemical Company
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| Tel: |
(800) 364-9897 |
| Email: |
cayman@caymanchem.com |
| Products Intro: |
Cas:1009104-85-1
ProductName:SMAD3 Inhibitor, SIS3
Brand: Caymanchem | Product Number: 15945 | Purity: ≥98%
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Smad3 Inhibitor manufacturers
- Inhibitor
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- $19.00 / 1T
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2024-05-11
- CAS:
- Min. Order: 1T
- Purity: 98%
- Supply Ability: 20T
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| | Smad3 Inhibitor Basic information |
| Product Name: | Smad3 Inhibitor | | Synonyms: | Smad3 Inhibitor;Smad3 Inhibitor, SIS3;SIS3 free base;SMAD3 Inhibtor, SIS 3;(E)-1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-3-pyrrolo[2,3-b]pyridyl)-2-propen-1-one;2-Propen-1-one, 1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-;SIS-3 free base,SIS3 free base;1-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one | | CAS: | 1009104-85-1 | | MF: | C28H27N3O3 | | MW: | 453.53 | | EINECS: | | | Product Categories: | Specific Inhibitor of Smad3, SIS3 | | Mol File: | 1009104-85-1.mol |  |
| | Smad3 Inhibitor Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.2 mg/ml | | form | A crystalline solid |
| | Smad3 Inhibitor Usage And Synthesis |
| Uses | SMAD3 Inhibitor, SIS3 selectively inhibits TGF-β and activin. It has been shown to reduce TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts. | | Definition | ChEBI: An enamide resulting from the formal condensation of the amino group of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline with the carboxy group of (2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acrylic
cid. |
| | Smad3 Inhibitor Preparation Products And Raw materials |
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