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Vasp Antibody

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Vasp Antibody manufacturers
Vasp Antibody Basic information
Product Name:Vasp Antibody
Synonyms:PRE-IMMUNE SERUM TO PAB TO VASODILATOR STIMULATED PHOSPHOPROTEIN;POLYCLONAL ANTIBODY TO VASP (HUMAN);MONOCLONAL ANTIBODY TO VASP (IE273);MONOCLONAL ANTIBODY TO VASP;VASP ANTIBODY;ANTISERUM TO VASP;ANTI-VASP;ANTI-VASP (HUMAN)
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MW:0
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Mol File:Mol File
Vasp Antibody Structure
Vasp Antibody Chemical Properties
storage temp. -20°C
form buffered aqueous solution
Safety Information
MSDS Information
Vasp Antibody Usage And Synthesis
UsesAnti-VASP (C-terminal) antibody produced in rabbit has been used in immunoblotting and immunofluorescence.
General DescriptionVasodilator stimulated phosphoprotein (VASP) is encoded by the gene mapped to human chromosome 19q13.32. The encoded protein belongs to the Ena/VASP protein family. VASP is characterized with an N-terminal EVH1 domain, C-terminal EVH2 domain and proline-rich region.
Biochem/physiol ActionsVasodilator stimulated phosphoprotein (VASP) acts as an actin-polymerization regulator and plays a vital role in regulation of cell migration by interacting with Migfilin, a cell-extracellular matrix (ECM) adhesion protein. Elevated expression of VASP contributes to the development of breast cancer (BC). Hence, this protein can be used as a potential biomarker for BC metastasis. Phosphorylation of VASP by protein kinase A (PKA) at phosphorylation site S157 aids in localization of cell periphery into focal adhesions, but phosphorylation of VASP at S239 and T278 aids in regulation of F-actin assembly.
Vasp Antibody Preparation Products And Raw materials
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