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| Benzamidine Hcl Basic information |
| Benzamidine Hcl Chemical Properties |
Melting point | 86-88 °C(lit.) | storage temp. | 2-8°C | solubility | DMF: 25 mg/ml DMSO: 25 mg/ml Ethanol: 10 mg/ml PBS (pH 7.2): 3 mg/ml | form | Powder | color | White to off-white | PH | 4.0 to 6.5(50g/L, 25 ℃) | Water Solubility | soluble | BRN | 3594959 | Stability: | Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily | InChIKey | LZCZIHQBSCVGRD-UHFFFAOYSA-N | CAS DataBase Reference | 1670-14-0(CAS DataBase Reference) | EPA Substance Registry System | Benzenecarboximidamide, monohydrochloride (1670-14-0) |
| Benzamidine Hcl Usage And Synthesis |
Uses | Benzamidine is a drug used to treat painful and inflammatory conditions of the oral cavity, such as infections and gingivitis. | Mechanism of action | Benzamidine HCl is a reversible inhibitor of trypsin, trypsin-like enzymes, and serine proteases. A concentration of approximately 1 mM is used for general protease inhibition. To inhibit proteases from yeast, a range of 0.5 to 4.0 mM is used and it is for the most part interchangeable with pepstatin A. | in vitro | Benzamidine hydrochloride (50 μM) reduces [3H]thymidine incorporation in fibroblasts, suggesting dependency on an active catalytic site. Benzamidine hydrochloride reduces the ability of tryptase to stimulate collagen synthesis. |
| Benzamidine Hcl Preparation Products And Raw materials |
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