| Company Name: |
Wuhan Yida Pharmaceutical Co., Ltd
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| Tel: |
+86-13401188533 +86-13476102740 |
| Email: |
3451936732@qq.com |
| Products Intro: |
Cas:57-63-6
ProductName:Ethinyl Estradiol
Purity: 99+ | Package: 1kg;10kg
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| Company Name: |
|
| Tel: |
|
| Email: |
poltd@panchsheelorgancis.in |
| Products Intro: |
Cas:57-63-6
ProductName:ETHINYL ESTRADIOL
Purity: 99% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
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- Ethinyl Estradiol
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- $70.00 / 1g
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2024-08-27
- CAS:57-63-6
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 30
- Estradiol
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- $7.99 / 1KG
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2022-02-25
- CAS:50-28-2
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1000tons
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| Product Name: | Ethinyl Estradiol | | Synonyms: | 19-NORPREGNA-1,3,5(10)-TRIEN-20-YNE-3,17ALPHA-DIOL;19-NOR-1,3,5[10],17ALPHA-PREGNATRIEN-20-YNE-3,17-DIOL;1,3,5(10)-ESTRATRIEN-17-ALPHA-ETHYNYL-3,17-BETA-DIOL;ACETENYL ESTRADIOL;17ALPHA-ETHYNYL-DELTA1,3,5(10)-ESTRA-TRIENE-3,17BETA-DIOL;17-ALPHA-ETHYNLESTRADIOL;17ALPHA-ETHYNYL-1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL;17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol | | CAS: | 57-63-6 | | MF: | C20H24O2 | | MW: | 296.41 | | EINECS: | 200-342-2 | | Product Categories: | Steroids;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Alcohols and Derivatives;Acetylenes;Biochemistry;Functionalized Acetylenes;Hydroxysteroids;Inhibitors;Hormone Drugs;progestogen estrogen;ESTINYL;57-63-6 | | Mol File: | 57-63-6.mol |  |
| | Ethinyl Estradiol Chemical Properties |
| Melting point | 182-183 °C(lit.) | | Boiling point | 378°C (rough estimate) | | density | 1.0944 (rough estimate) | | refractive index | -30 ° (C=0.4, Pyridine) | | Fp | 9℃ | | storage temp. | room temp | | solubility | ethanol: 50 mg/mL, clear, slightly yellow | | pka | pKa 10.32 (Uncertain) | | form | Solid | | color | White to Light yellow to Light orange | | Merck | 14,3734 | | BRN | 2419975 | | BCS Class | 3/1 | | InChIKey | BFPYWIDHMRZLRN-SLHNCBLASA-N | | CAS DataBase Reference | 57-63-6(CAS DataBase Reference) | | NIST Chemistry Reference | Ethinyl estradiol(57-63-6) | | EPA Substance Registry System | Ethinyl estradiol (57-63-6) |
| | Ethinyl Estradiol Usage And Synthesis |
| Description | Ethinyl Estradiol is a fine white to creamy white powder. It is a synthetic steroid. Used in combination with progestogen as an oral contraceptive. 17alpha-ethynylestradiol is a 3-hydroxy steroid that is estradiol substituted by a ethynyl group at position 17. It is a xenoestrogen synthesized from estradiol and has been shown to exhibit high estrogenic potency on oral administration. It has a role as a xenoestrogen. It is a 17-hydroxy steroid, a terminal acetylenic compound and a 3-hydroxy steroid.
| | Uses |
Drospirenone; Ethinyl Estradiol: prevents ovulation and pregnancy. It may also be used to treat acne and premenstrual dysphoric disorder (PMDD). It belongs to a group of medications called oral contraceptives. It is a combination of the hormones estrogen and progestin.
| | Toxicology | Ethinyl estradiol (EO, a semisynthetic 17 β-oestradiol) is the highly potent estrogen. The median lethal dose (LD50) of EO has been determined to be more than 1000 μg/kg body weight, orally in female albino rats. EO caused the cytotoxicity, leading to cancer in the uterus and ovary of female albino rat. Further, EO @ 500 μg/kg, orally, weekly for 8 and 12 weeks has been reported to cause liver damage in female albino rat. | | Synthesis | Ethinyl estradiol, 17α-ethinyl-1,3,5(10)-estratrien-3-17β-diol (28.1.26), is made either by condensing estrone with acetylene in the presence of potassium hydroxide (Favorskii reaction), or by reacting sodium acetylenide in liquid ammonia with estrone.
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| | Ethinyl Estradiol Preparation Products And Raw materials |
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