Nhs Ester

Nhs Ester manufacturers

Nhs Ester Basic information
Product Name:Nhs Ester
Synonyms:CARBOXYFLUORESCEIN DIACETATE, NHS ESTER;5(6)-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXY-SUCCINIMIDE ESTER;5(6)-CARBOXYFLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER;5-CARBOXYFLUORESCEIN-NHS DIACETATE;5-CARBOXY-DI-O-ACETYLFLUORESCEIN N-SUCCINIMIDYL ESTER;5-CARBOXYFLUORESCEIN DIACETATE-N-HYDROXYSUCCINIMIDE ESTER;5-CARBOXY-FLUORESCEIN DIACETATE N-SUCCINIMIDYL ESTER;5-FAM-NHS DIACETATE
CAS:150347-59-4
MF:C29H19NO11
MW:557.46
EINECS:
Product Categories:marker;Fluorescent;Xanthene;Aromatics;Fluorescent Labels & Indicators;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:150347-59-4.mol
Nhs Ester Structure
Nhs Ester Chemical Properties
Melting point 152-154 °C(lit.)
storage temp. -20°C
solubility DMF: soluble
pka6.45(at 25℃)
form Solid
color Off-white to yellow
PH RangeWeak green ' uorescence (6.0) to strong green ' uorescence (7.2)
λmax<300nm
Major ApplicationDiagnosis of cancer, restricting HIV replication, antiinflammatory agent, detecting bacteria, cell proliferation assays
InChIKeyQSWYNOQSGMUDQZ-UHFFFAOYSA-N
Safety Information
WGK Germany 3
8-10-21
HS Code 32129000
MSDS Information
ProviderLanguage
SigmaAldrich English
Nhs Ester Usage And Synthesis
Chemical Properties5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is Off-white to light yellow powder
Uses5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN is a Non-fluorescent cell permeant amine-reactive probe for long term tracing of cell.
UsesA 5(6)-Carboxyfluorescein (C178215) derivative used as a flurorescent probe. 5(6)-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester is used to monitor lymphocyte proliferation by covalently labelling long-lived intracellular molecules with fluorescent dye.
UsesAmine-reactive succinimidyl ester can potentially be used for long-term pH studies of live cells, producing a conjugate with the pH-sensitive properties of carboxyfluorescein.
General Description5-(and-6)-Carboxyfluorescein diacetate N-succinimidyl ester (CFSE) is a fluorescent dye, which is membrane permeable. It labels cells by covalently binding to intracellular molecules. CFSE is used to track lymphocyte migration and proliferation.
Biochem/physiol Actions5(6)-Carboxyfluorescein diacetate N-succinimidyl ester is used as an indicator for esterase activity.
Nhs Ester Preparation Products And Raw materials
Tag:Nhs Ester(150347-59-4) Related Product Information
6-Carboxyfluorescein 5-CFDA N-succinimidyl ester 6-Carboxyfluorescein 3’,6’-Diacetate N-Succinimidyl Ester BIS-(4-METHOXYPHENYL) ETHER 4-(2 5-DIMETHOXYPHENYL)BUTYRIC ACID 97 TERT-BUTYL 3-BUTENOATE 3,5-BIS(CHLOROMETHYL)PYRIDINE HCL 5(6)-(N-SUCCINIMIDYLOXYCARBONYL)-3',6',O,O'-DIACETYLFLUORESCEIN GAMMA-PHENYL-GAMMA-BUTYROLACTONE 4,4'-Oxydiphenol 6-CARBOXYFLUORESCEIN DIACETATE 5(6)-Carboxyfluorescein Fluorescein diacetate 5(6)-CFDA 5-CARBOXYFLUORESCEIN DIACETATE 4-(3-ACETOXYPHENYL)-1-BUTENE 4-(2,5-DIMETHOXYPHENYL)-1-BUTENE ACRYLOYL-X, SE