Company Name: |
TargetMol Chemicals Inc.
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Tel: |
4008200310 |
Email: |
marketing@tsbiochem.com |
Products Intro: |
Product Name:MAX-40279 hemifumarate CAS:2388506-43-0 Package:2mg/RMB 1540;5mg/RMB 2610;25mg/RMB 9160
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| Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Basic information |
| Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Chemical Properties |
storage temp. | -20°C, away from moisture | solubility | DMF : 1.96 mg/mL (3.53 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C) | form | Solid | color | Off-white to light yellow |
| Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Usage And Synthesis |
Biological Activity | MAX-40279 hemifumarate is a dual and potent inhibitor of FLT3 kinase and FGFR kinase. MAX-40279 hemifumarate has the potential for the research of acute myelogenous leukemia (AML) (extracted from patent WO2021180032)[1]. | References | [1]. Yuguang Wang, et al. Novel Therapeutic Methods. Patent WO2021180032A1. |
| Thieno[3,2-d]pyrimidin-2-amine, 7-(4-fluoro-2-methoxyphenyl)-6-methyl-N-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-, (2E)-2-butenedioate (2:1) Preparation Products And Raw materials |
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