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2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)-

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2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)- Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:MBRI-001；MBRI001. BPI-2358-d;plinabulin-d;MBRI 001;NPI-2358-d
CAS:2054938-28-0
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)- Basic information
Product Name:2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)-
Synonyms:2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)-;MBRI 001;MBRI-001;MBRI001. BPI-2358-d;NPI-2358-d;plinabulin-d
CAS:2054938-28-0
MF:C19H20N4O2
MW:336.4
EINECS:
Product Categories:
Mol File:2054938-28-0.mol
2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)- Structure
2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)- Chemical Properties
Safety Information
MSDS Information
2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)- Usage And Synthesis
DescriptionMBRI-001 is a deuterium-substituted plinabulin derivative as a potent anti-cancer agent. MBRI-001 exhibited better pharmacokinetic characteristics than that of plinabulin. Additionally, its antitumor activity is in a low nanomolar level for a variety of cancer cell lines and high activity against human NCI-H460 xenograted in mice intravenous administration. Importantly, continuous administration of MBRI-001 exhibited lower toxicity compared to docetaxel.
2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)- Preparation Products And Raw materials
Tag:2,5-Piperazinedione, 3-[[5-(1,1-dimethylethyl)-1H-imidazol-4-yl]methylene-d]-6-(phenylmethylene)-, (3Z,6Z)-(2054938-28-0) Related Product Information