| Company Name: |
ShangHai Biochempartner Co.,Ltd
|
| Tel: |
177-54423994 17754423994 |
| Email: |
2853530910@QQ.com |
| Products Intro: |
Product Name:LMTK3 inhibitor C28
CAS:2764850-23-7
Purity:98% HPLC LCMS Package:100mg;500mg;1g
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| Company Name: |
Shanghai Chaolan Chemical Technology Center
|
| Tel: |
QQ:65489617 15618227136 |
| Email: |
info@SuperLan-chem.com |
| Products Intro: |
Product Name:LMTK3-IN-1
CAS:2764850-23-7
Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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LMTK3 inibitor C28 manufacturers
- LMTK3-IN-1
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- $48.00 / 1mg
-
2024-11-06
- CAS:2764850-23-7
- Min. Order:
- Purity: 100%
- Supply Ability: 10g
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| | LMTK3 inibitor C28 Basic information |
| Product Name: | LMTK3 inibitor C28 | | Synonyms: | LMTK3 inibitor C28;LMTK3-IN-1;6-(Pyridin-4-yl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazine;4-{3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-yl}pyridine | | CAS: | 2764850-23-7 | | MF: | C18H11F3N4O | | MW: | 356.31 | | EINECS: | | | Product Categories: | | | Mol File: | 2764850-23-7.mol |  |
| | LMTK3 inibitor C28 Chemical Properties |
| solubility | Soluble to 50 mM in DMSO and to 20 mM in ethanol | | form | Solid | | color | Light yellow to yellow |
| | LMTK3 inibitor C28 Usage And Synthesis |
| Biological Activity | C28 is a potent lemur tyrosine kinase 3 (LMTK3) inhibitor (IC50 = 67 nM). Disrupts interaction of LMTK3 and HSP90 leading to degradation of LMTK3. Also inhibits CLK, DYRK1α, IRAK4 and HIPK2 (IC50 values are 5 nM, 6 nM, 41 nM and 48 nM respectively). C28 inhibits growth and increases apoptosis in breast cancer cell lines (IC50 = 6.5-14.77 μM) and reduces growth of tumors in xenograft and transgenic mouse models of breast cancer. Also reduces levels of ERα. | | storage | Store at -20°C |
| | LMTK3 inibitor C28 Preparation Products And Raw materials |
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