Log in | Join Free | china | japan | germany

fomivirsen

Request For Quotation
fomivirsen Suppliers list
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:Fomivirsen sodium
CAS:160369-77-7
Purity:99% Package:5KG;1KG
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:Fomivirsen sodium
CAS:160369-77-7
Purity:>=99.0% Package:$284.9/1mg;$628.9/5mg;$1005.9/10mg;Bulk package Remarks:99.0%
Company Name: LGM Pharma  
Tel: 1-(800)-881-8210
Email: inquiries@lgmpharma.com
Products Intro: Product Name:FoMivirsen
CAS:160369-77-7
Purity:Typically NLT 98%
Company Name: CLEARSYNTH LABS LTD.  
Tel: +91-22-45045900
Email: sales@clearsynth.com
Products Intro: Product Name:Fomivirsen Sodium
CAS:160369-77-7
fomivirsen Basic information
Product Name:fomivirsen
Synonyms:
CAS:160369-77-7
MF:C204H243N63Na20O114P20S20
MW:7122.03654
EINECS:
Product Categories:
Mol File:160369-77-7.mol
fomivirsen Structure
fomivirsen Chemical Properties
storage temp. Store at -20°C
form Solid
color White to off-white
Safety Information
MSDS Information
fomivirsen Usage And Synthesis
DescriptionFomivirsen Sodium was launched as Vitravene in the US and is indicated for the local treatment of cytomegalovirus (CMV)-induced retinitis in AIDS patients. It consists of a phosphorothioate oligonucleotide (PS) comprised of a sequence of 21 nucleotides. Fomivirsen is synthesized using solid-phase phosphoramidite chemistry. Fomivirsen inhibits human CMV replication by a antisense mechanism : it targets an immediate early mRNA of cytomegalovirus, inhibiting the expression of two regulatory proteins. Fomivirsen was the most advanced first-generation PS drug candidate in human clinical trials and was the first agent based on antisense technology to reach the market. In normal human dermal fibroblast cells, Fomivirsen inhibited AD169 human CMV replication by more than 90%, at a concentration of 5μM ; it showed greater hCMV replication inhibitor properties than ganciclovir in several experimental models.
OriginatorIsis Pharmaceuticals (US)
Brand nameVitravene
fomivirsen Preparation Products And Raw materials
Tag:fomivirsen(160369-77-7) Related Product Information