| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Caveolin-1
Purity:affinity isolated antibody, buffered aqueous solution Package:200μL Remarks:C4490
|
|
| | ANTI-CAVEOLIN 1 Basic information |
| Product Name: | ANTI-CAVEOLIN 1 | | Synonyms: | ANTI-VIP21;ANTI-VIP21, RABBIT;ANTI-CAVEOLIN 1;ANTI-CAVEOLIN-1(N-20);ANTI-CAVEOLIN-1 RABBIT;Anti-Caveolin-1 antibody produced in rabbit;Anti-Caveolin-1, Anti-VIP21;Anti-Caveolin-1-Cy3 antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-CAVEOLIN 1 Structure]() |
| | ANTI-CAVEOLIN 1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| | ANTI-CAVEOLIN 1 Usage And Synthesis |
| Uses | Monoclonal Anti-Caveolin-1 antibody has been used in western blot analysis. | | Uses | Anti-Caveolin-1 antibody produced in rabbit has been used in:
- immunoblotting
- immunofluorescence
- immunohistochemistry
| | General Description | Caveolin, a 20-24 kDa integral transmembrane protein, has been identified as a principal component of caveolae membranes. Caveolin (also termed VIP21) exists in several isoforms termed caveolin-1, caveolin-2 and caveolin-3. Caveolin-1 (CAV1) (20- 22 kDa) can exist as two isoforms, caveolin-1α and -1β due to alternative splicing of the mRNA. Caveolin-1 and -2 have similar tissue distribution. | | Biochem/physiol Actions | Caveolin can simultaneously recognize GPI-linked proteins and interact directly with a number of caveolae associated downstream signaling molecules, such as H-Ras, hetero-trimeric G-proteins, annexin-II, epidermal growth factor receptor (EGFR), protein kinase C, src-family tyrosine kinases and nitric oxide synthase (NOS) isoforms. Caveolin-1 participates in angiogenesis and is expected to play a major role in the growth and evolution of cancer. It participates in glucose metabolism by controlling the expression of glucose transporters. |
| | ANTI-CAVEOLIN 1 Preparation Products And Raw materials |
|