| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-GRP78/BiP (ET-21)
Purity:IgG fraction of antiserum, buffered aqueous solution Package:200μL Remarks:G9043
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| Company Name: |
Shanghai Huzhen Industrial Co., LTD
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| Tel: |
021-60345367 13916550749 |
| Email: |
sales@shzbio.com |
| Products Intro: |
Product Name:GDF10
Purity:> 99% Package:50ul/RMB 1138;100ul/RMB 1880;200ul/RMB 2900 Remarks:BIP; BMP 3b; BMP3B; Bone inducing protein; Bone morphogenetic protein 3b; GDF 10; GDF-10; growth differentiation factor 1
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| | ANTI-BIP Basic information |
| Product Name: | ANTI-BIP | | Synonyms: | ANTI-IMMUNOGLOBULIN HEAVY CHAIN BINDING PROTEIN;ANTI-GRP78/BIP (ET-21);ANTI-GRP78/BIP (GL-19);ANTI-GRP78, RAT;ANTI-GRP78, RAT (RABBIT);ANTI-GRP78;ANTI-GRP78 (645-354) RABBIT PAB;ANTI-GLUCOSE REGULATED PROTEIN 78 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-BIP Structure]() |
| | ANTI-BIP Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 21/22 | | Safety Statements | 36/37 | | WGK Germany | 3 |
| | ANTI-BIP Usage And Synthesis |
| Uses | Anti-GRP78/BiP (GL-19) antibody produced in rabbit has been used in:
- western blotting
- immunocytochemistry
- immunohistochemistry
| | General Description | GRP78/BiP is a Ca2+-binding molecular chaperone located in the endoplasmic reticulum (ER). It is a highly conserved protein. | | Biochem/physiol Actions | GRP78 (78-kDa glucose-regulated protein) is essential for cell viability. GRP78/BiP is induced by stress-inducing agents or by conditions that adversely affect endoplasmic reticulum(ER) function, including oxidative stress, chemical toxicity, Ca2+ ionophores, inhibition of the ER Ca2+ -ATPase, inhibitors of glycosylation and hypoxia. GRP78/BiP is critical for maintenance of Ca2+ homeostasis and the prevention of apoptosis. GRP78/BiP levels are reduced in Alzheimer′s disease brains and the decreased expression of GRP78/BiP is found associated with mis-sense mutations in presenilin-1 (PS-1). |
| | ANTI-BIP Preparation Products And Raw materials |
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