| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-EIF4E antibody produced in rabbit
Purity:affinity isolated antibody Package:100UL Remarks:SAB2100666-100UL
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:affinity isolated antibody, lyophilized powder
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573 Basic information |
| Product Name: | Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573 | | Synonyms: | Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573;Anti-eIF4E antibody produced in rabbit | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573 Structure]() |
| | Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573 Chemical Properties |
| | Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573 Usage And Synthesis |
| Uses | All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org)and as a result, are supported by the most extensive characterization in the industry.
The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit . | | General Description | The translational factor eukaryotic translation initiation factor 4E (eIF4E), also known as mRNA cap-binding protein(CBP) or EIF4E1 is a central component of translation initiation and regulation in eukaryotic cells. eIF4E exists as both a free form and as part of a multiprotein complex termed eIF4F. Although mainly expressed in the cytoplasm, a fraction of eIF4E localizes to the nucleus, and some of the biological effects of eIF4E might be effected by a nuclear function. | | Biochem/physiol Actions | The translational factor eukaryotic translation initiation factor 4EeIF4E regulates the recruitment of mRNAs to the ribosome. Its interaction with mRNA cap structure enhances its binding to eIF4G and 40S ribosomal subunit. eIF4Eplays a role in diverse biological processes including embryonic development, cell cycle progression, synaptic plasticity, and cancer. eIF4E is subjected to tight regulation both at the level of its expression and by control of its activity by phosphorylation mitogen-activated protein kinase (MAPK) interacting protein kinases (by the Mnk kinase). Human P bodies contain the cap-binding protein eIF4E and the related factor eIF4E-transporter (eIF4E-T; eIF4ENIF1), suggesting novel roles for these proteins in targeting mRNAs for 5′ to 3′ degradation. |
| | Anti-CBP, Anti-eIF4E1, Anti-eIF4EL1, Anti-eIF4F, Anti-Eukaryotic intiation factor 4E, Anti-MGC111573 Preparation Products And Raw materials |
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