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| | (20S)-3β,20-Bis(dimethylamino)pregna-5-ene Basic information |
| | (20S)-3β,20-Bis(dimethylamino)pregna-5-ene Chemical Properties |
| Melting point | 140-141° (from acetone) | | alpha | D20 -37° (c = 1.9); D22 -36° (c = 1.112 in CHCl3); D22 -17° (c = 1.050 in methanol) |
| | (20S)-3β,20-Bis(dimethylamino)pregna-5-ene Usage And Synthesis |
| Description | A pregnene alkaloid found in the bark of Holarrhena antidysenterica Wall. and
also present in the leaves of Sarcococca pruni!ormis Lindl., the base forms colour_x0002_less crystals from Me2CO and has [α]20D - 37° (c 1.90, CHCl3), - 17° (c 1.OS,
MeOH). It contains three methyl groups and two dimethylamino groups in the
molecule. The alkaloid is characterized as the crystalline perchlorate, m.p. 277-
9°C (dec.) or the picrate, m.p. 228-230°C. The structure has been established as
3 ,20 -bis (dimethylamino)pregn-S-ene. It is identical with saracodinine. | | Definition | ChEBI: Kurchessine is an aza-steroid. | | References | Tschesche, Wiensz., Chem. Ber., 91, lS04 (19S8)
Tschesche, Otto., ibid, 95, 1144 (1962)
Chatterjee et aI., Tetrahedron Lett., 67 (1965)
Structure:
Labler, Sorm., Collect. Czech. Chem. Commun., 28,2345 (1963) |
| | (20S)-3β,20-Bis(dimethylamino)pregna-5-ene Preparation Products And Raw materials |
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