153804-05-8
中文名称 | 153804-05-8 |
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中文同义词 | 普拉沙坦;化合物 T16573 |
英文名称 | PRATOSARTAN |
英文同义词 | PRATOSARTAN;FW 7203;4(3H)-Cycloheptimidazolone, 5,6,7,8-tetrahydro-2-propyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- |
CAS号 | 153804-05-8 |
分子式 | C25H26N6O |
分子量 | 426.51 |
EINECS号 | |
相关类别 | |
Mol文件 | 153804-05-8.mol |
结构式 |
153804-05-8 性质
沸点 | 692.9±65.0 °C(Predicted) |
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密度 | 1.32±0.1 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 溶于二甲基亚砜 |
酸度系数(pKa) | 4.15±0.10(Predicted) |
Pratosartan 是一种选择性的血管紧张素 II 受体拮抗剂。
angiotensin II receptor
Pratosartan, which is an orally active angiotensin II (AII) antagonist, exhibiting selective and potent antagonistic activity to AT 1 subtype. Pratosartan is a new angiotensin II type 1 receptor blocker. Pratosartan is an effective and well tolerated antihypertensive drug, and may has beneficial effect on hypertensive patients with some metabolic disorders.