|
| CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) Basic information |
Product Name: | CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) | Synonyms: | CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1);VTP-27999 2,2,2-trifluoroacetate;VTP-27999, (2,2,2-trifluoroacetate) (1:1);methyl N-[2-[(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate,2,2,2-trifluoroacetic acid;N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamic acid methyl ester 2,2,2-trifluoroacetate;VTP-27999 (trifluoroacetate salt);VTP-27999 TFA;VTP 27999; 2;2;2-TRIFLUOROACETATE;VTP27999; 2;2;2-TRIFLUOROACETATE;VTP-27999 | CAS: | 1013937-63-7 | MF: | C28H42ClF3N4O7 | MW: | 639.11 | EINECS: | | Product Categories: | | Mol File: | 1013937-63-7.mol | |
| CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) Chemical Properties |
solubility | H2O : 10 mg/mL (15.65 mM; Need ultrasonic) | form | Powder | color | Colorless to light yellow |
| CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) Usage And Synthesis |
Uses | VTP 27999 Trifluoroacetate is a highly potent and selective renin inhibitor. | storage | Store at -20°C |
| CARBAMIC ACID, N-[2-[(R)-(3-CHLOROPHENYL)[(3R)-1-[[[(2S)-2-(METHYLAMINO)-3-[(3R)-TETRAHYDRO-2H-PYRAN-3-YL]PROPYL]AMINO]CARBONYL]-3-PIPERIDINYL]METHOXY]ETHYL]-, METHYL ESTER, 2,2,2-TRIFLUOROACETATE (1:1) Preparation Products And Raw materials |
Raw materials | (R)-tert-butyl 3-((R)-(3-chlorophenyl)(2-hydroxyethoxy)Methyl)piperidine-1-carboxylate-->1-Piperidinecarboxylic acid, 3-[(R)-(2-aMinoethoxy)(3-chlorophenyl)Methyl]-, 1,1-diMethylethyl ester, (3R)--->(R)-tert-butyl 3-((R)-(2-azidoethoxy)(3-chlorophenyl)Methyl)piperidine-1-carboxylate-->3-[(3-Chloro-phenyl)-(2-methanesulfonyloxy-ethoxy)-methyl]-piperidine-1-carboxylic acid tert-butyl ester-->3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)--->3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-5-hydroxypentyl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)--->3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-5-[(Methylsulfonyl)oxy]pentyl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)--->1-Piperidinecarboxylic acid, 3-[(R)-(3-chlorophenyl)hydroxyMethyl]-, 1,1-diMethylethyl ester, (3R)--->1-Piperidinecarboxylic acid, 3-[(R)-(3-chlorophenyl)[2-[(Methoxycarbonyl)aMino]ethoxy]Methyl]-, 1,1-diMethylethyl ester, (3R)--->CarbaMic acid, N-[(1S,3R)-1,3-bis(hydroxyMethyl)-5-hexen-1-yl]-, 1,1-diMethylethyl ester-->3-Oxazolidinecarboxylic acid, 4-[(2R)-2-(hydroxyMethyl)-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)--->(R)-tert-butyl 3-(3-chlorobenzoyl)piperidine-1-carboxylate-->1-Piperidinecarboxylic acid, 3-[(MethoxyMethylaMino)carbonyl]-, 1,1-diMethylethyl ester, (3R)- |
|