| Company Name: |
Adamas Reagent, Ltd.
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| Tel: |
400-6009262 16621234537 |
| Email: |
chenyj@titansci.com |
| Products Intro: |
Product Name:N-Dodecanoyl-L-Homoserine Lactone
CAS:137173-46-7
Purity:98%+ Package:100mg;250mg;1g
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| Product Name: | DDHL | | Synonyms: | C12-HOMOSERINE LACTONE;DDHL;N-DODECANOYL-L-HOMOSERINE LACTONE;C12-HSL, dDHL, N-Dodecanoyl-L-hoMoserine lactone;Dodecanoyl-L-hoMoserine lactone;C12-HSL;N-[(3S)-Tetrahydro-2-oxo-3-furanyl]dodecanamide;N-Lauroyl-L-homoserine lactone | | CAS: | 137173-46-7 | | MF: | C16H29NO3 | | MW: | 283.41 | | EINECS: | | | Product Categories: | | | Mol File: | 137173-46-7.mol |  |
| Melting point | 128 °C(Solv: ethyl acetate (141-78-6)) | | Boiling point | 485.8±34.0 °C(Predicted) | | density | 1.00±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Chloroform: 10 mg/ml; DMF: 1 mg/ml; DMSO: 1 mg/ml | | form | A crystalline solid | | pka | 14.71±0.20(Predicted) | | color | White to off-white | | optical activity | [α]/D -25±5°, c = 0.2 in methanol | | BRN | 9281984 |
| Risk Statements | 53 | | WGK Germany | 3 |
| Uses | Dodecanoyl-L-homoserine lactone is a modulator of cell communication and regulation. | | Uses | Dodecanoyl-L-homoserine lactone is an active quorum sensing modulator first recognised in Sinorhizobium meliloti. N-Acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains. | | Uses | Dodecanoyl-L-homoserine lactone was confirmed to be an active quorum sensing modulator first recognised in Sinorhizobium meliloti. N-Acylhomoserine lactones have been detected in hundreds of bacterial species and, while the homologues vary between species and strains, the homoserine lactones are the major chemical modulators of within and between cell communication and regulation. The most significant variable defining the function of the homoserine lactone is the length of the acyl chain, with shorter chains displaying opposing actions to the longer chains. | | Definition | ChEBI: An N-acyl-L-homoserine lactone having dodecanoyl as the acyl substituent. | | Biochem/physiol Actions | N-Dodecanoyl-L-homoserine lactone is a member of N-acyl-homoserine lactone family. N-Acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella, and are involved in quorum sensing, cell to cell communication among bacteria; for reviews see. Bacterial intercellular communication has become a target for the development of new anti-virulence drugs, and a research focus for the prevention of biofilm formation. |
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