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| | Bis(2,4-dimethylphenyl)amine Basic information |
| Product Name: | Bis(2,4-dimethylphenyl)amine | | Synonyms: | N-(2,4-Dimethylphenyl)-2,4-dimethylbenzenamine;bis(2,4-diMethylphenyl)aMine;N-(2,4-Dimethylphenyl)-2,4-dimethylbenzemine;2,2′4,4′-tetramethyldiphenylamine;N-(2,4-Dimethylphenyl)-2,4-dimethylaniline;2,4,2',4'- tetramethyl diphenylamine;Benzenamine, N-(2,4-dimethylphenyl)-2,4-dimethyl-;Di-2,4-xylylamine | | CAS: | 19616-28-5 | | MF: | C16H19N | | MW: | 225.33 | | EINECS: | 1533716-785-6 | | Product Categories: | | | Mol File: | 19616-28-5.mol |  |
| | Bis(2,4-dimethylphenyl)amine Chemical Properties |
| Melting point | 57.0 to 61.0 °C | | Boiling point | 310°C(lit.) | | density | 1.021 | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | powder to crystal | | pka | 1.43±0.50(Predicted) | | color | White to Orange to Green | | InChI | InChI=1S/C16H19N/c1-11-5-7-15(13(3)9-11)17-16-8-6-12(2)10-14(16)4/h5-10,17H,1-4H3 | | InChIKey | MAINCNYZMOMWRA-UHFFFAOYSA-N | | SMILES | C1(NC2=CC=C(C)C=C2C)=CC=C(C)C=C1C | | CAS DataBase Reference | 19616-28-5 |
| | Bis(2,4-dimethylphenyl)amine Usage And Synthesis |
| Chemical Properties | White powder | | Uses | Bis(2,4-dimethylphenyl)amine is a pharmaceutical intermediate widely used in food, health care products, cosmetics and other fields. | | Synthesis |
2,4-dimethylaniline 2.67 g (molecular weight 121,22 mmol) was added to a 100 ml reaction flask under nitrogen.2.68 g of 2,4-dimethylbromobenzene (molecular weight 184,20 mmol), 5.76 g of sodium tert-butoxide (molecular weight 96,60 mmol), Pd2(dba)3 183 mg (molecular weight 916, 0.2 mmol), P(tBu)3 121 mg (molecular weight 202, 0.6 mmol).Anhydrous toluene 50 ml.After the addition, the oil bath was slowly heated to reflux reaction, and TLC monitored the reaction end, and the reaction was completed in 10 hours. Cooled, quenched with water, and extracted with 50ml of dichloromethane, the organic phase dried over anhydrous MgSO4, and the organic phase evaporated to dryness; the resulting solid was separated by column chromatography to give a white solid Bis(2,4-dimethylphenyl)amine 3.8g, molecular weight 225, 85percent yield.
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| | Bis(2,4-dimethylphenyl)amine Preparation Products And Raw materials |
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