GYY 4137 Morpholine salt manufacturers
|
| GYY 4137 Morpholine salt Basic information |
Product Name: | GYY 4137 Morpholine salt | Synonyms: | GYY 4137 MORPHOLINE SALT;GYY 4137;(4-Methoxyphenyl)morpholino-phosphinodithioic acid compound with morpholine;P-(4-Methoxyphenyl)-P-4-morpholinylphosphinodithioic acid morpholine salt;GYY4137;GYY-4137;GYY 4137;morpholin-4-ium (4-methoxyphenyl)(morpholino)phosphinodithioate;(4-methoxyphenyl)-morpholin-4-yl-sulfanylidene-sulfido-λ5-phosphane,morpholin-4-ium;4-Methoxyphenyl(morpholino)phosphinodithioate morpholinium salt | CAS: | 106740-09-4 | MF: | C15H25N2O3PS2 | MW: | 376.474361 | EINECS: | | Product Categories: | | Mol File: | 106740-09-4.mol | |
| GYY 4137 Morpholine salt Chemical Properties |
Melting point | 164-166℃ | solubility | DMF: 20 mg/ml; DMSO: 15 mg/ml; PBS (pH 7.2): 3 mg/ml | form | White solid. | color | White |
| GYY 4137 Morpholine salt Usage And Synthesis |
Description | Hydrogen sulfide (H2S) is a gaseous mediator which, like nitric oxide (NO), has numerous profound actions in mammalian physiology. GYY 4137 is a water-soluble, slow-releasing hydrogen sulfide (H2S) donor. When given intravenously, it demonstrates vasodilator and anti-hypertensive activity in rats, in either the acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Intravenous GYY 4137 also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation. | Uses | GYY 4137 is a slow releasing hydrogen sulfide donor. | Uses | Hydrogen sulfide (H2S) is a gaseous mediator which, like nitric oxide (NO), has numerous profound actions in mammalian physiology. GYY 4137 is a water-soluble, slow-releasing hydrogen sulfide (H2S) donor. When given intravenously, it demonstrates vasodilator and anti-hypertensive activity in rats, in either the acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Intravenous GYY 4137 also protects against endotoxic shock in rats, inhibiting tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 production and reducing NF-κB activation, iNOS and cyclooxygenase-2 expression, and NO and prostaglandin E2 generation.[Cayman Chemical] | storage | +4°C |
| GYY 4137 Morpholine salt Preparation Products And Raw materials |
|