- Brincidofovir
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- $0.00 / 1g
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2024-03-12
- CAS:444805-28-1
- Min. Order: 1g
- Purity: 98% HPLC
- Supply Ability: 1kg
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| | CMX 001 Basic information |
| Product Name: | CMX 001 | | Synonyms: | Brincidofovir;CMX001(Brincidofovir);CMX 001;HDP-cidofovir;Hexadecyloxypropyl-cidofovir;(S)-[2-(4-amino-2-oxo-1,2-dihydro-1-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methylphosphonic acid 3-(hexadecyloxy)propyl monoester;[[(S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid mono[3-(hexadecyloxy)propyl] ester;Phosphonic acid, P-[[(1S)-2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]-, mono[3-(hexadecyloxy)propyl] ester | | CAS: | 444805-28-1 | | MF: | C27H52N3O7P | | MW: | 561.69 | | EINECS: | | | Product Categories: | | | Mol File: | 444805-28-1.mol |  |
| | CMX 001 Chemical Properties |
| Melting point | > 177° C (dec.) | | Boiling point | 688.6±65.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly, Sonicated), Ethanol (Slightly, Heated, Sonicated), Methanol (Sli | | form | Solid | | pka | 2.40±0.10(Predicted) | | color | White to Off-White | | Stability: | Hygroscopic |
| | CMX 001 Usage And Synthesis |
| Uses | Brincidofovir is an antiviral inhibitor, working against BK polymavirus replication in primary human urothelial cells. Cytostatic, cytotoxic agent. | | Biological Activity | cmx001 is a broad spectrum antiviral agent [1].cmx001 has been reported to be active in vitro against a broad range of viruses from all five families of dsdna viruses infecting human with ec50 values of 0.02μm, 0.0004μm, 17μm , 0.045μm and 0.07μm for adenovirus, herpesvirus, papillomavirus, polyomavirus and orthopoxvirus, respectively. in addition, cmx001 has been revealed to arrest disease progression by inhibiting viral dna replication and thereby reducing viral burden. apart from these, initial studies has been demonstrated the efficacy of cmx001 for pre-exposure and post-exposure prophylaxis in mouse, rabbit, cynomolgus monkeys and human [1]. | | references | [1]lanier r1, trost l, tippin t, lampert b, robertson a, foster s, rose m, painter w, o'mahony r, almond m, painter g.development of cmx001 for the treatment of poxvirus infections. viruses. 2010 dec; 2(12):2740-2762. |
| | CMX 001 Preparation Products And Raw materials |
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