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Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-

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Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:WHI-P180
CAS:211555-08-7
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: career henan chemical co
Tel: +86-0371-86658258 +8613203830695
Email: sales@coreychem.com
Products Intro: Product Name:Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
CAS:211555-08-7
Purity:98% Package:1KG;1USD
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:WHI-P180
CAS:211555-08-7
Package:10mg Remarks:BOC Sciences also provides custom synthesis services for WHI-P180.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:WHI-P180
CAS:211555-08-7
Purity:97.74% Package:2mg;33USD|5mg;53USD|10mg;79USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Henan Alfa Chemical Co., Ltd
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Products Intro: CAS:211555-08-7
Purity:98% Package:5g, 25g, 100g, 500g, 1kg, 25kg

Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- manufacturers

  • WHI-P180
  • WHI-P180 pictures
  • $39.00 / 1mg
  • 2024-11-19
  • CAS:211555-08-7
  • Min. Order:
  • Purity: 97.74%
  • Supply Ability: 10g
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Basic information
Product Name:Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-
Synonyms:Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-;3-[(6,7-Dimethoxy-4-quinazolinyl)amino]phenol;Janex 3;3-(6,7-dimethoxyquinazolin-4-ylamino)phenol;3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol (Related Reference);WHI P180;JANEX3;WHIP180;JANEX-3;WHI-P180(Janex 3);WHI-P180, >98%
CAS:211555-08-7
MF:C16H15N3O3
MW:297.31
EINECS:
Product Categories:Inhibitors
Mol File:211555-08-7.mol
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Structure
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Chemical Properties
Boiling point 476.5±40.0 °C(Predicted)
density 1.336±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility DMSO : 25 mg/mL (84.09 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka9.58±0.10(Predicted)
color White to off-white
Safety Information
MSDS Information
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Usage And Synthesis
Biological ActivityWHI-P180 is an inhibitor of multiple kinases with IC50 values of 4.5 nM and 66 nM for RET (c-RET) and KDR, respectively.
in vivo

WHI-P180 is also an active inhibitor of IgE-mediated mast cell responses. The elimination half-life of WHI-P180 in CD-1 mice (BALB/c mice) following iv, ip, or po administration is less than 10 min. Systemic clearance of WHI-P180 is 6742 mL/h/kg in CD-I mice and 8188 mL/h/kg in BALB/c mice. Notably, WHI-P180, when administered in two consecutive nontoxic ip bolus doses of 25 mg/kg, inhibits IgE/antigen-induced vascular hyperpermeability in a well-characterized murine model of passive cutaneous anaphylaxis.

target
TargetValue
RET
(Cell-free assay)		 4.5 nM
KDR
(Cell-free assay)		 66 nM
Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]- Preparation Products And Raw materials
Tag:Phenol, 3-[(6,7-diMethoxy-4-quinazolinyl)aMino]-(211555-08-7) Related Product Information
4-(3'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE, HCL WEHI-345 JAK3 INHIBITOR II JAK3 INHIBITOR I 4-AMINO-3-CYANO-1,2,5,6-TETRAHYDROPYRIDINE WH-4-023 7-BROMO-1,2,3,4-TETRAHYDRO-QUINOLINE HYDROCHLORIDE 3,4-Dimethoxyphenethylamine 2-Methylsulfonyl-4,6-dimethoxypyrimidine WHI-P97 4-PHENYLAMINO-6,7-DIMETHOXYQUINAZOLINE JAK3 Inhibitor