| Company Name: |
Haoyuan Chemexpress Co., Ltd.
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021-58950125 |
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info@chemexpress.com |
| Products Intro: |
Product Name:Mutant IDH1 inhibitor
CAS:1429180-08-4
Purity:>98% Package:2170RMB/2mg
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| | Mutant IDH1 inhibitor Basic information |
| Product Name: | Mutant IDH1 inhibitor | | Synonyms: | Mutant IDH1 inhibitor;(4S)-3-[2-[[(1S)-1-[4-[(4-Acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-2-oxazolidinone;SCHEMBL14831541;2-Oxazolidinone, 3-[2-[[(1S)-1-[4-[(4-acetyl-1-piperazinyl)methyl]phenyl]ethyl]amino]-4-pyrimidinyl]-4-(1-methylethyl)-, (4S)-;Mutant IDH1 inhibitor,Mutant IDH-1 inhibitor,inhibit,Isocitrate Dehydrogenase (IDH),Inhibitor;(S)-3-(2-(((S)-1-(4-((4-Acetylpiperazin-1-yl)methyl)phenyl)ethyl)amino)pyrimidin-4-yl)-4-isopropyloxazolidin-2-one | | CAS: | 1429180-08-4 | | MF: | C25H34N6O3 | | MW: | 466.58 | | EINECS: | | | Product Categories: | | | Mol File: | 1429180-08-4.mol |  |
| | Mutant IDH1 inhibitor Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: ≥ 34 mg/mL (72.87 mM) | | form | Powder | | color | White to light yellow |
| | Mutant IDH1 inhibitor Usage And Synthesis |
| Description | Mutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM. | | in vitro | In Vitro:Mutant IDH1 inhibitor is a potent IDH1 R132H inhibitor, and used for the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer[1]. | | References | References:[1]. 3-Pyrimidin-4-yl-oxazolidin-2-ones as inhibitors of mutant IDH and their preparation. Patent WO 2013046136 A1 20130404 |
| | Mutant IDH1 inhibitor Preparation Products And Raw materials |
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