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3A Chemicals
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400-668-9898 |
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Products Intro: |
Product Name:L-Dab.HBr CAS:73143-97-2 Purity:98% Package:2535.00RMB/25g Remarks:A37767
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(S)-2,4-Diaminobutanoic acid hydrobromide manufacturers
- L-DABA hydrobromide
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- $41.00 / 100mg
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2024-11-19
- CAS:73143-97-2
- Min. Order:
- Purity: 99.11%
- Supply Ability: 10g
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| (S)-2,4-Diaminobutanoic acid hydrobromide Basic information |
| (S)-2,4-Diaminobutanoic acid hydrobromide Chemical Properties |
storage temp. | Sealed in dry,Room Temperature | form | Solid | color | White to off-white |
| (S)-2,4-Diaminobutanoic acid hydrobromide Usage And Synthesis |
Uses | L-DABA (L-2,4-Diaminobutyric acid) hydrobromide is a week GABA transaminase inhibitor with an IC50 of larger than 500 μM; exhibits antitumor activity in vivo and in vitro. | in vivo | Treatment with L-DABA hydrobromide results in 43.4% reduction of tumor growth[1]. L-DABA hydrobromide is a more effective inhibitor of GABA transaminase in vivo than in vitro[2]. | References | [1] Ronquist G, et al. Antitumor activity of L-2,4 diaminobuturic acid against mouse fibrosarcoma cells in vitro and in vivo. J Cancer Res Clin Oncol. 1980;96(3):259-68. DOI:10.1007/BF00408098 [2] Beart PM, et al. l-2,4-Diaminobutyric acid and the GABA system. Neurosci Lett. 1977 Jul;5(3-4):193-8. DOI:10.1016/0304-3940(77)90046-5 [3] Panasci L, et al. The cytolytic effect of L-2,4 diaminobutyric acid with malignant glioma cells and fibroblasts. Cancer Chemother Pharmacol. 1988;21(2):143-4. DOI:10.1007/BF00257361 |
| (S)-2,4-Diaminobutanoic acid hydrobromide Preparation Products And Raw materials |
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