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(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate)

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Products Intro: Product Name:(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate)
CAS:868539-99-5
Purity:>=98% Package:10kg;50kg;100kg
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Products Intro: Product Name:(S)-Methyl 2-((S)-2-((S)-2-amino-4-phenylbutanamido)-4-methylpentanamido)-3-phenylpropanoate 2,2,2-trifluoroacetate
CAS:868539-99-5
Purity:98% Min. Package:5KG;1KG
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Products Intro: Product Name:(S)-Methyl 2-((S)-2-((S)-2-amino-4-phenylbutanamido)-4-methy...
CAS:868539-99-5
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Products Intro: Product Name:(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate)
CAS:868539-99-5
Purity:98% Package:100mg, 250mg, 1g, 5g
(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate) Basic information
Product Name:(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate)
Synonyms:(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate);(S)-Methyl-2-((S)-2-((S)-2-aMino-4-phenylbutanaMido)-4-Methyl;(S)-Methyl 2-((S)-2-((S)-2-aMino-4-phenylbutanaMido)-4-MethylpentanaMido)-3-phenylpropanoate trifluoroacetic acid;(αS)-α-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine Methyl Ester Mono(trifluoroacetate);(αS)-α-Amino-4-nitrobenzenepropanamideS)-a-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine Methyl Este;(S)-Methyl 2-((S)-2-((S)-2-amino-4-phenylbutanamido)-4-methy...;L-Phenylalanine, (aS)-a-aminobenzenebutanoyl-L-leucyl-, methyl ester,mono(trifluoroacetate);(S)-Methyl 2-((S)-2-((S)-2-amino-4-phenylbutanamido)-4-methylpentanamido)-3-phenylpropanoate 2,2,2-trifluoroacetate
CAS:868539-99-5
MF:C28H36F3N3O5
MW:551.5977496
EINECS:
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Mol File:868539-99-5.mol
(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate) Structure
(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate) Chemical Properties
Melting point 219-221°C
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Pale Yellow
Safety Information
MSDS Information
(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate) Usage And Synthesis
Uses(αS)-α-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine Methyl Ester Mono(trifluoroacetate) is an intermediate of Carfilzomib (C183460) which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate) Preparation Products And Raw materials
Raw materialsmethyl 3-phenyl-L-alaninate-->Boc-HPh-Leu-Phe-OMe-->Trifluoroacetic acid-->N-(tert-Butoxycarbonyl)-L-phenylalanine
Tag:(alphaS)-alpha-Aminobenzenebutanoyl-L-leucyl-L-phenylalanine methyl ester mono(trifluoroacetate)(868539-99-5) Related Product Information
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide Carfilzomib Impurity 2 CarfilzoMib IMpurity 5 (S)-benzyl 2-((S)-2-((S)-2-amino-4-phenylbutanamido)-4-methylpentanamido)-3-phenylpropanoate hydrochloride (S)-N-((S)-1-(((S)-2,6-Dimethyl-3-oxohept-1-en-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide (S)-2-((S)-2-Acetamido-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide Carfilzomib Related Impurity (S)-benzyl 2-((S)-4-methyl-2-((S)-2-(2-morpho lino acetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoate (S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide (S)-2-((S)-4-Methyl-2-((R)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamido)-3-phenylpropanoic acid Carfilzomib Impurity 15 CarfilzoMib IMpurity 4 (S)-N-((S)-1-(((2R,4S)-1-((1H-Benzo[d][1,2,3]triazol-1-yl)oxy)-2-hydroxy-2,6-dimethyl-3-oxoheptan-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)-4-methyl-2-((S)-2-(2-morpholinoacetamido)-4-phenylbutanamido)pentanamide Carfilzomib Impurity 9 (S)-benzyl 2-((S)-2-amino-4-methylpentanamido)-3-phenylpropanoate hydrochloride Carfilzomib Impurity 5 TFA Salt Carfilzomib Impurity 4 (N-Oxide Impurity) (R)-4-Methyl-N-((S)-1-(((S)-4-Methyl-1-((R)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide