| Company Name: |
Codow Chemical Co.,Ltd.
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| Tel: |
18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:3?,27-dihydroxy-5-cholesten-7-one
CAS:240129-30-0
Purity:>99% Package:1MG;2.5MG;5MG
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| Company Name: |
Chengdu Dianchun Technology Co., Ltd
|
| Tel: |
400-1166-196 18502815961 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:3,27-dihydroxy-5-cholesten-7-one
CAS:240129-30-0
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| | 3,27-dihydroxy-5-cholesten-7-one Basic information |
| Product Name: | 3,27-dihydroxy-5-cholesten-7-one | | Synonyms: | 3,27-dihydroxy-5-cholesten-7-one;7-keto-27-hydroxycholesterol;Cholest-5-en-7-one, 3,26-dihydroxy-, (3β,25R)-;3,27 dihydroxy-5 cholesteren-7 one;3, 27-dihydroxy-5-cholestene-7-one;3β,27-dihydroxy-5-cholesten-7-one | | CAS: | 240129-30-0 | | MF: | C27H44O3 | | MW: | 416.64 | | EINECS: | | | Product Categories: | | | Mol File: | 240129-30-0.mol |  |
| | 3,27-dihydroxy-5-cholesten-7-one Chemical Properties |
| Boiling point | 554.5±33.0 °C(Predicted) | | density | 1.08±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 14.68±0.70(Predicted) | | form | powder |
| | 3,27-dihydroxy-5-cholesten-7-one Usage And Synthesis |
| Uses | 7-Keto-27-hydroxycholesterol is used in the study of biochemical methods for the extraction and quantitative analysis of sterols and secosteroids from human plasma using combination of HPLC-MS and GC-MS. | | Biological Activity | 7-keto-27-hydroxycholesterol (7-OC) acts as an agonist for the smoothened (SMO) protein of Hedgehog (Hh) signalling pathway, which is vital for proper cell differentiation in embryonic tissue. It elicits strong affinity to SMO compared to 7β,(25R)26-dihydroxycholesterol (7β,26-diHC). 7-OC is reduced to 7β,(25R)26-dihydroxycholesterol (7β,26-diHC) by reactive oxygen species (ROS). |
| | 3,27-dihydroxy-5-cholesten-7-one Preparation Products And Raw materials |
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