Company Name: |
BOC Sciences
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Tel: |
16314854226 |
Email: |
info@bocsci.com |
Products Intro: |
Product Name:Diminutol CAS:361431-33-6 Purity:98% Package:1G;10G;100G
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Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
Tel: |
400-9205774 |
Email: |
sales@glpbio.cn |
Products Intro: |
Product Name:Diminutol CAS:361431-33-6 Purity:>98% Package:1mg;10mg;50mg;100mg;
|
Company Name: |
DC Chemicals
|
Tel: |
021-58447131 13564518121 |
Email: |
sales@dcchemicals.com |
Products Intro: |
Product Name:Diminutol CAS:361431-33-6 Purity:98% HPLC Package:100mg,250mg,1g
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- Diminutol
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- $950.00 / 5mg
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2024-10-24
- CAS:361431-33-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| Diminutol Basic information |
Product Name: | Diminutol | Synonyms: | Diminutol;1-Butanol, 2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-, (2R)-;NG72 | CAS: | 361431-33-6 | MF: | C19H26N6OS | MW: | 386.51 | EINECS: | | Product Categories: | | Mol File: | 361431-33-6.mol | |
| Diminutol Chemical Properties |
storage temp. | Store at -20°C | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml | form | A crystalline solid |
| Diminutol Usage And Synthesis |
Description | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization. | Uses | Diminutol is a cell-permeable purine analog that inhibits NQ01 and blocks mitotic spindle assembly. | Uses | Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 μM), to destabilize microtubules and disrupt mitosis. At 50 μM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin polymerization.[Cayman Chemical] |
| Diminutol Preparation Products And Raw materials |
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