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Hs 27

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Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: Product Name:2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27
CAS:1562024-11-6
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:HS-27
CAS:1562024-11-6
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Xi'an MC Biotech, Co., Ltd.
Tel: 029-89275612 +8618991951683
Email: mcbio_sales@163.com
Products Intro: Product Name:2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27
CAS:1562024-11-6
Purity:98% Package:1G;10G;1KG,5KG,10KG
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:HS-27
CAS:1562024-11-6
Purity:98% Package:$100.9/1mg;$276.9/5mg;$442.9/10mg;$1004.9/50mg;$1088.9/25mg;$1406.9/100mg;Bulk p Remarks:98%
Company Name: Wuhan Jingkang en Biomedical Technology Co., Ltd
Tel: +8613720134139
Email: orders@jknbiochem.com
Products Intro: Product Name:2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27
CAS:1562024-11-6
Purity:0.98 Package:10G:100G
Hs 27 Basic information
Product Name:Hs 27
Synonyms:Hs 27;1562024-11-7;2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thio,HS-27;Benzamide, 2-[[21-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-21-thioxo-4,7,10,13,16-pentaoxa-20-azaheneicos-1-yl]amino]-4-(4,5,6,7-tetrahydro-3,6,6-trimethyl-4-oxo-1H-indazol-1-yl)-;HS27;HS-27;HS 27;2-((1-((3',6'-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9,-XANTHEN]-5-YL)AMINO)-1-THIOXO-6,9,12,15,18-PENTAOXA-2-AZAHENICOSAN-21-YL)AMINO)-4-(3,6,6-TRIMETHYL-4-OXO-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL)BENZAMIDE,HS-27;HS27,HS 27;2-((1-((3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9,-xanthen]-5-yl)amino)-1-thioxo-6,9,12,15,18-pentaoxa-2-azahenicosan-21-yl)amino)-4-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indazol-1-yl)benzamide,HS-27
CAS:1562024-11-6
MF:C52H60N6O12S
MW:993.13
EINECS:
Product Categories:
Mol File:1562024-11-6.mol
Hs 27 Structure
Hs 27 Chemical Properties
Boiling point 1095.1±75.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
storage temp. -196°C
solubility DMSO: 125 mg/mL (125.86 mM)
pka9.33±0.20(Predicted)
form Solid
color Yellow to orange
Safety Information
MSDS Information
Hs 27 Usage And Synthesis
Biological ActivityHS-27, a fluorescent Hsp90 inhibitor, detects Hsp90 expression on the surface of intact tissue specimens. It consists of the core elements of SNX-5422, an Hsp90 inhibitor linked via a PEG linker to a fluorescein derivative (fluorescein isothiocyanate or FITC) that binds to peripherally expressed Hsp90 combine.
in vitroHS-27 labels all receptor subtypes of breast cancer, but not normal cells, and specifically binds to Hsp90 expressed on the surface of breast cancer cells before being internalized.
target

HSP90

Hs 27 Preparation Products And Raw materials
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