(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:BOC-DAP-NE
CAS:160800-65-7
Purity:98% Package:10MG;50MG;100MG,1G,5G,10G.100G
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Products Intro: Product Name:BOC-Dap-NE
CAS:160800-65-7
Purity:99.43% Package:10mg;30USD|25mg;45USD|50mg;64USD Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
CAS:160800-65-7
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CAS:160800-65-7
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Products Intro: Product Name:BOC-DAP-NE
CAS:160800-65-7
Purity:98% Min. Package:5KG;1KG
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Basic information
Product Name:(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate
Synonyms:(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate;Boc-Dap-NE;1-Pyrrolidinecarboxylic acid, 2-[(1R,2R)-3-[[(1R,2S)-2-hydroxy-1-methyl-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-, 1,1-dimethylethyl ester, (2S)-;N-Boc-Dap-NE;Antibody-drug conjugates linkers,inhibit,ADC Linkers,BOC Dap NE,Inhibitor,BOCDapNE;(2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-N-[(1S,2R)-1-hydroxy-1-phenyl-2-propyl]-3-methoxy-2-methylpropanamide;tert-butyl (S)-2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate;tert-butyl (2S)-2-[(1R,2R)-2-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]carbamoyl}-1-methoxy-2-methylethyl]pyrrolidine-1-carboxylate
CAS:160800-65-7
MF:C23H36N2O5
MW:420.54
EINECS:
Product Categories:ADC LINKER;ADCs Linkers;ADCs
Mol File:160800-65-7.mol
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Structure
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Chemical Properties
Melting point 55-57 °C
Boiling point 589.1±50.0 °C(Predicted)
density 1.125±0.06 g/cm3(Predicted)
solubility DMSO: 100 mg/mL (237.79 mM)
pka13.66±0.20(Predicted)
form Solid
color White to off-white
Water Solubility Water: < 0.1 mg/mL (insoluble)
InChIKeyXJDVGABQIFOWFC-SCQOQHIRSA-N
SMILESN1(C(OC(C)(C)C)=O)CCC[C@H]1[C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C1=CC=CC=C1)=O
Safety Information
MSDS Information
(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Usage And Synthesis
Uses

Boc-Dap-NE, a dipeptide, is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

Biological ActivityBoc-Dap-NE is a dipeptide used as a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
target

Cleavable

(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate Preparation Products And Raw materials
Tag:(S)-tert-butyl 2-((1R,2R)-3-(((1S,2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidine-1-carboxylate(160800-65-7) Related Product Information