- Thiol-PEG6-t-butyl ester
-
- $0.00 / 500mg
-
2024-03-27
- CAS:1818294-40-4
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
|
| | Thiol-PEG6-t-butyl ester Basic information |
| Product Name: | Thiol-PEG6-t-butyl ester | | Synonyms: | Thiol-PEG6-t-butyl ester;HS-PEG6-CH2CH2COOtBu;SH-PEG6-CH2CH2COOtBu;HS-PEG6-CH2CH2-Boc;4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-mercapto-, 1,1-dimethylethyl ester | | CAS: | 1818294-40-4 | | MF: | C19H38O8S | | MW: | 426.57 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1818294-40-4.mol |  |
| | Thiol-PEG6-t-butyl ester Chemical Properties |
| Boiling point | 488.8±45.0 °C(Predicted) | | density | 1.072±0.06 g/cm3(Predicted) | | pka | 9?+-.0.10(Predicted) |
| | Thiol-PEG6-t-butyl ester Usage And Synthesis |
| Biological Activity | HS-PEG6-CH2CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Thiol-PEG6-t-butyl ester Preparation Products And Raw materials |
|