| Company Name: |
Pharmacodia (Beijing) Co.,Ltd
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| Tel: |
+86-400-851-9921 |
| Email: |
sales@pharmacodia.com |
| Products Intro: |
Product Name:UCM05
CAS:1094451-90-7
Package:10Mg-100g
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| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:G 28UCM
CAS:1094451-90-7
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Product Name: | UCM05 | | Synonyms: | UCM05;G 28UCM;3-(3,4,5-Trihydroxybenzoyloxy)naphthalen-1-yl 3,4,5-trihydroxybenzoate;Benzoic acid, 3,4,5-trihydroxy-, 1,1'-(1,3-naphthalenediyl) ester;UCM05(G 28UCM) | | CAS: | 1094451-90-7 | | MF: | C24H16O10 | | MW: | 464.38 | | EINECS: | | | Product Categories: | | | Mol File: | 1094451-90-7.mol |  |
| | UCM05 Chemical Properties |
| Boiling point | 895.1±65.0 °C(Predicted) | | density | 1.652±0.06 g/cm3(Predicted) | | solubility | DMF: 10 mg/ml; DMSO: 5 mg/ml; Ethanol: 12 mg/ml; Ethanol:PBS (pH 7.2) (1:40): 0.02 mg/ml | | form | A crystalline solid | | pka | 7.50±0.25(Predicted) |
| | UCM05 Usage And Synthesis |
| Uses | G 28UCM is a fatty acid synthase inhibitor with anticancer activity, novel inhibitor of fatty acid synthase with anticancer activity. | | Uses | UCM05 is an inhibitor of fatty acid synthase that strongly suppresses the growth of human breast cancer cell lines (IC50 = 21 μM for SK-BR-3 cells). It does not alter carnitine palmitoyltransferase 1 activity or induce weight loss in mice. UCM05 can reduce cleavage of poly(ADP-ribose) polymerase, phosphorylation of HER2, Akt, and ERK1/2, and growth of established xenografts in vivo. UCM05 also blocks the GTP-binding site of the cell division protein FtsZ from Bacillus, preventing bacterial division.[Cayman Chemical] | | storage | Store at -20°C |
| | UCM05 Preparation Products And Raw materials |
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