| Company Name: |
Guangzhou Isun Pharmaceutical Co., Ltd
|
| Tel: |
020-39119399 18927568969 |
| Email: |
isunpharm@qq.com |
| Products Intro: |
Product Name:1279713-77-7
CAS:1279713-77-7
Purity:98% Package:1G; 5G; 25G; 100G; 1KG; 5KG
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CU CPT 4a manufacturers
- TLR3-IN-1
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- $48.00 / 1mg
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2024-11-14
- CAS:1279713-77-7
- Min. Order:
- Purity: 97.77%
- Supply Ability: 10g
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| | CU CPT 4a Basic information |
| Product Name: | CU CPT 4a | | Synonyms: | CU CPT 4a;N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine;D-Phenylalanine, N-[(3-chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-;TLR3-IN-1;TLR3/dsRNA complex,inhibit,CU-CPT 4a,TNF-α,protein-RNA interaction,IL-1β,TLR-3-IN-1,Inhibitor,TLR3 IN 1,TLR3IN1,Toll-like Receptor (TLR);(3-Chloro-6-fluorobenzo[b]thiophene-2-carbonyl)-D-phenylalanine;TLR3-IN-1, 10 mM in DMSO | | CAS: | 1279713-77-7 | | MF: | C18H13ClFNO3S | | MW: | 377.82 | | EINECS: | | | Product Categories: | | | Mol File: | 1279713-77-7.mol |  |
| | CU CPT 4a Chemical Properties |
| storage temp. | Store at 4°C | | solubility | <37.78mg/ml in DMSO | | form | solid | | color | White |
| | CU CPT 4a Usage And Synthesis |
| Biological Activity | cu cpt 4a is a selective tlr3 inhibitor with ic50 of 3.44 μm in raw 264.7 cells. it can inhibit tlr3/dsrna complex-mediated downstream signaling pathways and inhibit the production of tnf-α and il-1β in whole cells. it reduces the mortality of crypt cells in mice and reduces gastrointestinal syndrome.[1]. cheng k, wang x, yin h. small-molecule inhibitors of the tlr3/dsrna complex. journal of the american chemical society, 2011, 133(11): 3764-3767.[2]. blockade of tlr3 protects mice from lethal radiation-induced gastrointestinal syndrome. nature communications, 2014, 5. | | storage | Store at +4°C |
| | CU CPT 4a Preparation Products And Raw materials |
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