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WRR483

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WRR483 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:WRR-483
CAS:1076088-50-0
Purity:0 Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
Company Name: BOC Sciences  
Tel: 16314854226
Email: info@bocsci.com
Products Intro: Product Name:WRR483
CAS:1076088-50-0
WRR483 Basic information
Product Name:WRR483
Synonyms:WRR483;1-Piperazinecarboxamide, N-[(1S)-4-[(aminoiminomethyl)amino]-1-[[[(1S)-1-(2-phenylethyl)-3-(phenylsulfonyl)-2-propen-1-yl]amino]carbonyl]butyl]-4-methyl-
CAS:1076088-50-0
MF:C29H41N7O4S
MW:583.75
EINECS:
Product Categories:
Mol File:1076088-50-0.mol
WRR483 Structure
WRR483 Chemical Properties
Safety Information
MSDS Information
WRR483 Usage And Synthesis
DescriptionWRR-483, an analogue of K-11777, is a potent and selective cysteine protease inhibitor with trypanocidal activity in cell culture and animal model with comparable efficacy to K11777. WRR-483 demonstrates good potency against cruzain with sensitivity to pH conditions and high efficacy in the cell culture assay. Furthermore, WRR-483 also eradicates parasite infection in a mouse model of acute Chagas' disease. WRR-483 binds covalently to the active site cysteine of the protease in a similar manner as other vinyl sulfone-based inhibitors. WRR-483 has potential to be developed as a treatment for Chagas' disease.
WRR483 Preparation Products And Raw materials
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