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BOC Sciences
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info@bocsci.com |
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Product Name:CMP5
CAS:1030021-40-9
Purity:99% Remarks:CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell response
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| Product Name: | CMP5 | | Synonyms: | CMP-5 hydrochloride
(PRMT5-IN-5);CMP5;CMP-5 hydrochloride;CMP 5 hydrochloride,CMP5 hydrochloride | | CAS: | 1030021-40-9 | | MF: | C21H22ClN3 | | MW: | 351.88 | | EINECS: | | | Product Categories: | | | Mol File: | 1030021-40-9.mol |  |
| Description | CMP5 is a potent and selective PRMT5 Inhibitor. CMP5 showed to occupy hPRMT5 catalytic site and block symmetrically dimethylated S2Me-H4R3 & S2Me-H3R8 with no effect on the asymmetric methylation of H4R3 in lymphoblastoid cell lines at 40 μM. CMP-5 shows promise as a novel therapeutic_x000D_
approach for B-cell lymphomas. |
| | CMP5 Preparation Products And Raw materials |
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