1-(1,2-二氧代-3,3-二甲基戊基)-2(S)-2吡咯烷甲酸 CAS#: 186268-78-0

1-(1,2-二氧代-3,3-二甲基戊基)-2(S)-2吡咯烷甲酸

中文名称	1-(1,2-二氧代-3,3-二甲基戊基)-2(S)-2吡咯烷甲酸
中文同义词	1-(1,2-二氧代-3,3-二甲基戊基)-2(S)-2吡咯烷甲酸;(2S)-1-(1,2-二氧代-3,3-二甲基戊基)-2-吡咯烷甲酸;化合物GPI-1485;(S)-1-(3,3-二甲基-2-氧代戊酰基)吡咯烷-2-甲酸
英文名称	(2S)-1-(1',2'-DIOXO-3',3'-DIMETHYL-PENTYL)-2-PYRROLIDINE-CARBOXYLIC ACID
英文同义词	(2S)-1-(1',2'-DIOXO-3',3'-DIMETHYL-PENTYL)-2-PYRROLIDINE-CARBOXYLIC ACID;(2S)-1-(3,3-Dimethyl-2-oxopentanoyl)-pyrrolidine-2-carboxylic acid;GPI-1485;L-Proline, 1-(3,3-dimethyl-1,2-dioxopentyl)-;GPI-1485 L;neurofunctional,regeneration,Inhibitor,ligand,stroke,GPI-1485,GPI 1485,inhibit,immunophilin,neural,GM 1485,GM-1485,GPI1485
CAS号	186268-78-0
分子式	C12H19NO4
分子量	241.28
EINECS号
相关类别	吡咯类;Prolines
Mol文件	186268-78-0.mol
结构式

GPI-1485 (GM1485) 是一种免疫抑制剂的特异性亲免蛋白配体，促进中风后的神经功能改善和神经再生。

GPI-1485 (GM1485; 100 μM) induces cellular reprogramming and neural cell induction in normal human dermal fibroblasts (NHDF).

Cell Viability Assay

Cell Line:	Normal human dermal fibroblasts (NHDF) ^[1]
Concentration:	100 μM
Incubation Time:
Result:	Induced cellular reprogramming and neural cell induction.

GPI-1485 (GM1485; 5 mg/kg; intraperitoneal injection; 6-week period of daily) improves long-term neurological recovery in rats.

Animal Model:	Adult male Wistar rats, weighing 250-300 g
Dosage:	5 mg/kg
Administration:	Intraperitoneal injection; daily; for a total of 42 days
Result:	Administration improved neurological function and is consistent with an upregulation of endogenous neurogenesis following stroke in rats.

海关编码	2933998090

更新日期	产品编号	产品名称	CAS号	包装	价格
2024/08/19	HY-136424	GPI-1485		1 mg	909元
2024/08/19	HY-136424	1-(1,2-二氧代-3,3-二甲基戊基)-2(S)-2吡咯烷甲酸 GPI-1485	186268-78-0	5mg	2000元