Company Name: |
Haoyuan Chemexpress Co., Ltd.
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Tel: |
021-58950125 |
Email: |
info@chemexpress.com |
Products Intro: |
Product Name:TAK-778 CAS:180185-61-9 Purity:0.98 Package:10mg
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Company Name: |
Wuxi AppTec
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Tel: |
022-59987777 13552403979 |
Email: |
jia_guoqiang@wuxiapptec.com |
Products Intro: |
Product Name:diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate CAS:180185-61-9 Purity:0.95 Package:100g
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| diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate Basic information |
Product Name: | diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate | Synonyms: | Phosphonic acid, P-[[4-[[[(6R,8S)-5,6,8,9-tetrahydro-8-methyl-9-oxothiepino[4,5-f]-1,3-benzodioxol-6-yl]carbonyl]amino]phenyl]methyl]-, diethyl ester;diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate | CAS: | 180185-61-9 | MF: | C24H28NO7PS | MW: | 505.52 | EINECS: | | Product Categories: | | Mol File: | 180185-61-9.mol | |
| diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate Chemical Properties |
Melting point | 181-182 °C | Boiling point | 742.3±60.0 °C(Predicted) | density | 1.334±0.06 g/cm3(Predicted) | storage temp. | Store at -20°C | solubility | Soluble in DMSO | pka | 13.12±0.70(Predicted) |
| diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate Usage And Synthesis |
Uses | TAK-778 is a derivative of Ipriflavone and is shown to induce bone growth in vitro and in vivo. Recently, it has been shown that TAK-778 can enhance osteoblast differentiation of human bone marrow cells via an estrogen receptor (ER)-dependent pathway. |
| diethyl 4-((6R,8S)-8-methyl-9-oxo-5,6,8,9-tetrahydrothiepino[4,5:4,5]benzo[1,2-d][1,3]dioxole-6-carboxamido)benzylphosphonate Preparation Products And Raw materials |
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