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Product Name:H2N-PEG11-CH2CH2COOH CAS:1616426-12-0 Purity:98% Package:按需包装
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H2N-PEG11-CH2CH2COOH manufacturers
- Amino-PEG11-acid
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- $0.00 / 1Kg
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2024-04-07
- CAS:1616426-12-0
- Min. Order: 1Kg
- Purity: 99.9%
- Supply Ability: 200tons
- Amino-PEG11-COOH
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- $0.00 / 250mg
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2024-03-23
- CAS:1616426-12-0
- Min. Order: 250mg
- Purity: >98.00%
- Supply Ability: 250mg
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| H2N-PEG11-CH2CH2COOH Basic information |
Product Name: | H2N-PEG11-CH2CH2COOH | Synonyms: | H2N-PEG11-CH2CH2COOH;Amino-PEG11-propionic acid;Amino-PEG11-COOH;Amino-PEG11-acid;H2N-PEG11-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34-Undecaoxahexatriacontanoic acid, 36 amino-;4,7,10,13,16,19,22,25,28,31,34-Undecaoxahexatriacontanoic acid, 36 amino- | CAS: | 1616426-12-0 | MF: | C25H51NO13 | MW: | 573.67 | EINECS: | | Product Categories: | | Mol File: | 1616426-12-0.mol | |
| H2N-PEG11-CH2CH2COOH Chemical Properties |
Boiling point | 637.6±55.0 °C(Predicted) | density | 1.125±0.06 g/cm3(Predicted) | pka | 4.28±0.10(Predicted) |
| H2N-PEG11-CH2CH2COOH Usage And Synthesis |
Biological Activity | Amino-PEG11-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | References | [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
| H2N-PEG11-CH2CH2COOH Preparation Products And Raw materials |
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