| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Product Name:Monoclonal Anti-S1P2, C-Terminal antibody produced in mouse
Remarks:~1 mg/mL, affinity isolated antibody, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL Basic information |
| Product Name: | ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL | | Synonyms: | ANTI-S1P2, C-TERMINAL;ANTI-S1P2, C-TERMINAL RABBIT;ANTI-ENDOTHELIAL CELL DIFFERENTIATION GENE-5, C-TERMINAL RABBIT;ANTI-EDG-5, C-TERMINAL RABBIT;ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL;Anti-EDG-5, Anti-Endothelial Cell Differentiation Gene 5;Anti-S1P2, C-Terminal antibody produced in rabbit;Anti-EDG-5, Anti-Endothelial Cell Differentiation Gene 5, C-Terminal | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL Structure]() |
| | ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | - |
| | ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL Usage And Synthesis |
| Uses | Monoclonal Anti-S1P2, C-Terminal antibody produced in mouse is suitable for western blotting at a working dilution of 1:1000 (1μg/mL) using human T lymphoblasts, ovarian tumor cells, epithelial cells, estrogen receptor positive breast carcinoma cells, human spleen and rat spleen or lung. | | Biochem/physiol Actions | Sphingosine-1-phosphate receptor 2 (S1PR2 or S1P2) is a human gene encodes a G protein-coupled receptor. It binds the lipid signaling molecule sphingosine 1-phosphate (S1P) and regulates vascular permeability along with S1P1. Activation of S1P2R in endothelial cells increases vascular permeability. It is a bioactive lysophospholipid capable of inducing a wide spectrum of biological responses. S1P acts as an intercellular mediator by interacting with the endothelial differentiation gene (EDG)/S1P family of G protein-coupled receptors. S1P2 receptor is involved in S1P-induced platelet aggregation and Rho kinase activation. Type 2 diabetes patient responds to S1P. |
| | ANTI-EDG-5 (ENDOTHELIAL CELL DIFFERENTIATION GENE 5), C-TERMINAL Preparation Products And Raw materials |
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