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TOPO I HUMAN

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TOPO I HUMAN Suppliers list
Company Name: Guangzhou Tomums Life Science Co., Ltd.  
Tel: 020-31155029 18902330969
Email: sales@tomums.cn
Products Intro: Product Name:Topoisomerase I human
Package:250UN
Company Name: Riedel-de Haen AG  
Tel: 800 558-9160
Email:
Products Intro: Purity:buffered aqueous glycerol solution, ≥2 units/μL
Company Name: SIGMA-RBI  
Tel: 800 736 3690 (Orders)
Email:
Products Intro:
TOPO I HUMAN Basic information
Product Name:TOPO I HUMAN
Synonyms:TOPO I HUMAN;TOPOISOMERASE I HUMAN;TOPO(R) I;Topoisomerase I from vaccinia virus
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
TOPO I HUMAN Structure
TOPO I HUMAN Chemical Properties
storage temp. -70°C
form liquid
Safety Information
Hazard Codes T
Risk Statements 61
Safety Statements 23-24/25-45-53
WGK Germany 1
MSDS Information
ProviderLanguage
SigmaAldrich English
TOPO I HUMAN Usage And Synthesis
UsesTopoisomerase I human has been used for Topoisomerase I assay for screening inhibitors.
General DescriptionTopoisomerase I (TOP1) is mapped to human chromosome 20q12. TOP1 is a 91 kDa type IB enzyme and consists of N-terminal highly charged domain, a core, linker domain and a C-terminal catalytic domain with Tyr-723 active site residue.
Biochem/physiol ActionsTopoisomerase I human (TOP1) interacts with DNA by wrapping and takes a bi-lobed conformation. TOPI is essential for normal development and transcriptional regulation. Variants in the TOP1 gene is observed in patients with colorectal cancer.
TOPO I HUMAN Preparation Products And Raw materials
Tag:TOPO I HUMAN Related Product Information
TOPOISOMERASE I