KEA1-97 manufacturers
- KEA1-97
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- $40.00 / 5mg
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2024-11-19
- CAS:2138882-71-8
- Min. Order:
- Purity: 98.7%
- Supply Ability: 10g
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| | KEA1-97 Basic information |
| Product Name: | KEA1-97 | | Synonyms: | KEA1-97;1,3,5-Triazin-2-amine, 4,6-dichloro-N-(4'-fluoro[1,1'-biphenyl]-4-yl)-;KEA1-97 >=98% (HPLC);4,6-Dichloro-N-(4'-fluoro-[1,1'-biphenyl]-4-yl)-1,3,5-triazin-2-amine;Apoptosis,KEA1 97,Proliferation,Apoptotic,Caspase,inhibit,KEA-1-97,DCTalkyne,KEA1-97,231MFP,Inhibitor,Selective,KEA197;KEA1-97, 10 mM in DMSO | | CAS: | 2138882-71-8 | | MF: | C15H9Cl2FN4 | | MW: | 335.16 | | EINECS: | | | Product Categories: | | | Mol File: | 2138882-71-8.mol |  |
| | KEA1-97 Chemical Properties |
| Boiling point | 530.3±52.0 °C(Predicted) | | density | 1.466±0.06 g/cm3(Predicted) | | storage temp. | 4°C, protect from light | | solubility | DMSO : 100 mg/mL (298.36 mM; Need ultrasonic) | | pka | 0.57±0.10(Predicted) | | form | Solid | | color | White to light yellow |
| | KEA1-97 Usage And Synthesis |
| Description | KEA1-97 is a Thioredoxin-Caspase 3 interaction disruptor. It was found to target lysine 72 of thioredoxin, inhibiting its interactions with caspase 3 and inducing apoptosis without affecting other thioredoxin activity. KEA1-97 induced apoptosis in breast cancer cells and treatment of immune-deficient SCID mice at 5 mg/kg ip impaired breast tumor xenograft growth. |
| | KEA1-97 Preparation Products And Raw materials |
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