CH7057288

CH7057288 Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:CH7057288
CAS:2095616-82-1
Purity:99.92% Package:1mg;51USD|5mg;122USD|10mg;198USD Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:4-Pyridinecarboxamide, 2-[2-[6,11-dihydro-6,6-dimethyl-8-[(methylsulfonyl)amino]-11-oxobenzo[b]naphtho[2,3-d]furan-3-yl]ethynyl]-N-(1,1-dimethylethyl)-6-methyl-
CAS:2095616-82-1
Purity:above 99% Package:1g;2USD
Company Name: Zhejiang J&C Biological Technology Co.,Limited
Tel: +1-2135480471 +1-2135480471
Email: sales@sarms4muscle.com
Products Intro: Product Name:CH7057288
CAS:2095616-82-1
Purity:99% Package:5KG;1KG Remarks:CH7057288
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:CH7057288
CAS:2095616-82-1
Purity:98% Package:5mg Remarks:V4146
Company Name: TargetMol Chemicals Inc.
Tel:
Email: support@targetmol.com
Products Intro: Product Name:CH7057288
CAS:2095616-82-1
Package:1 mg;10 mg;100 mg;25 mg;5 mg;50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

CH7057288 manufacturers

  • CH7057288
  • CH7057288 pictures
  • $51.00 / 1mg
  • 2024-11-19
  • CAS:2095616-82-1
  • Min. Order:
  • Purity: 99.92%
  • Supply Ability: 10g
CH7057288 Basic information
Product Name:CH7057288
Synonyms:CH7057288;4-Pyridinecarboxamide, 2-[2-[6,11-dihydro-6,6-dimethyl-8-[(methylsulfonyl)amino]-11-oxobenzo[b]naphtho[2,3-d]furan-3-yl]ethynyl]-N-(1,1-dimethylethyl)-6-methyl-;Inhibitor,Trk Receptor,CH7057288,inhibit,Tropomyosin related kinase receptor,CH 7057288,CH-7057288
CAS:2095616-82-1
MF:C32H31N3O5S
MW:569.67
EINECS:
Product Categories:
Mol File:2095616-82-1.mol
CH7057288 Structure
CH7057288 Chemical Properties
density 1.35±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO:34.0(Max Conc. mg/mL);59.68(Max Conc. mM)
form Solid
pka6.89±0.40(Predicted)
color Off-white to yellow
Safety Information
MSDS Information
CH7057288 Usage And Synthesis
Biological ActivityCH7057288 is a potent and selective TRK inhibitor with IC50 values of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.
in vitro

In cell-free kinase assays, CH7057288 has selective inhibitory activity against TRKA, TRKB and TRKC, and inhibits the proliferation of cells containing TRK fusions. It inhibits MAPK and E2F signaling pathways.

target< td style="border-bottom: 1px dotted #ccc;padding: 5px;"> TrkB
(Cell-free assay)
TargetValue
TrkA
(Cell-free assay)
1.1 nM
TrkC
(Cell-free assay)
5.1 nM
7.8 nM
CH7057288 Preparation Products And Raw materials
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