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K-604 dihydrochloride

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K-604 dihydrochloride Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Products Intro: Product Name:K-604 dihydrochloride
CAS:217094-32-1
Purity:98.00% Package:10 mg；100 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Products Intro: Product Name:K-604 dihydrochloride
CAS:217094-32-1
Purity:>=99.0% Package:$150.9/5mg;$240.9/10mg;$480.9/25mg;$750.9/50mg;$1150.9/100mg;Bulk package Remarks:99.0%
Company Name: Guangzhou Isun Pharmaceutical Co., Ltd  
Tel: 020-39119399 18927568969
Email: isunpharm@qq.com
Products Intro: Product Name:K-604
CAS:217094-32-1
Purity:98% (HPLC) Package:5MG; 25MG; 100MG; 1G
Company Name: Shanghai Rechem science Co., Ltd.  
Tel: 21-31433387 15618786686
Email: sales@rechemscience.com
Products Intro: Product Name:K-604 2HCl
CAS:217094-32-1
Purity:98% Package:0.1g;1g;5g;10g
Company Name: Fan De(Beijing) Biotechnology Co., Ltd.  
Tel: 15911056312
Email: liming@bio-fount.com
Products Intro: Product Name:K-604 dihydrochloride
CAS:217094-32-1
Purity:97.0% Package:5mg
K-604 dihydrochloride Basic information
Product Name:K-604 dihydrochloride
Synonyms:K-604 dihydrochloride;K-604 (K604);K-604 >=98% (HPLC);K-604 2HCl;2-(4-(2-((1H-Benzo[d]imidazol-2-yl)thio)ethyl)piperazin-1-yl)-N-(6-methyl-2,4-bis(methylthio)pyridin-3-yl)acetamide dihydrochloride;K604,K604 dihydrochloride,acyl-CoA:cholesterol acyltransferase,K-604,inhibit,K 604,Inhibitor,Diacylglycerol acyltransferase,Diglyceride acyltransferase,mono- acylglycerol acyltransferase,Acyltransferase,K 604 dihydrochloride
CAS:217094-32-1
MF:C23H31ClN6OS3
MW:539.17
EINECS:
Product Categories:
Mol File:217094-32-1.mol
K-604 dihydrochloride Structure
K-604 dihydrochloride Chemical Properties
storage temp. 2-8°C
solubility DMSO: 62.5 mg/mL (108.57 mM)
form Solid
color white to beige
Safety Information
MSDS Information
K-604 dihydrochloride Usage And Synthesis
Biological ActivityK-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with IC50 of 0.45±0.06 μM.
in vivoUsing F1B hamsters, an animal model susceptible to diet-induced hyperlipidemia and atherosclerosis, the effects of K-604 dihydrochloride on aortic lesion areas and plasma cholesterol levels are assessed.
target

ACAT-1

< span> 0.45 μM (IC 50 )

ACAT-2

102.85 μM (IC 50 )

K-604 dihydrochloride Preparation Products And Raw materials
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