| Company Name: |
Changzhou Chenhong Biotechnology Co., Ltd.
|
| Tel: |
0519-85788828 13775037613 |
| Email: |
sales@chemrenpharm.com |
| Products Intro: |
Product Name:S 14506 hydrochloride
CAS:286369-38-8
Purity:99% Package:50mg;100mg;250mg;500mg;1g;5g
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| Company Name: |
MedBioPharmaceutical Technology Inc
|
| Tel: |
021-69568360 18916172912 |
| Email: |
order@med-bio.cn |
| Products Intro: |
Product Name:S 14506 hydrochloride
CAS:286369-38-8
Purity:98% Package:50mg; 10mg Remarks:Medbio
|
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| | S 14506 hydrochloride Basic information |
| | S 14506 hydrochloride Chemical Properties |
| storage temp. | Desiccate at RT | | solubility | Soluble to 10 mM in ethanol and to 100 mM in DMSO | | form | Powder | | color | White to off-white |
| | S 14506 hydrochloride Usage And Synthesis |
| Uses | S 14506 Hydrochloride is a highly potent selective 5-HT1A receptor full agonist and is involved in neuromodulation as well as in treatment of hypertension | | Definition | ChEBI: 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide hydrochloride is a hydrochloride salt that is obtained by reaction of 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide with one equivalent of hydrogen chloride. Highly potent selective 5-HT1A receptor full agonist (pKi values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT2 and 5-HT3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo. It has a role as a serotonergic agonist and an anxiolytic drug. It contains a 4-fluoro-N-{2-[4-(7-methoxynaphthalen-1-yl)piperazin-1-yl]ethyl}benzamide(1+). |
| | S 14506 hydrochloride Preparation Products And Raw materials |
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