| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
|
| Products Intro: |
Product Name:InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem
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| | InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem Basic information |
| | InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem Chemical Properties |
| | InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem Usage And Synthesis |
| General Description | Potent, reversible, and cell-permeable proteasome inhibitor (Ki = 4 nM).Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex without affecting its ATPase or isopeptidase activities. Activates c-Jun N-terminal kinase (JNK1) which initiates apoptosis. Inhibits NF-κBactivation (IC50 = 3 μM). This material is ≥95% pure by HPLC. A material with ≥98% purity by HPLC (Cat. No. 474791) and the solid form of this compound (Cat. No. 474787) are also available. | | Biochem/physiol Actions | Cell permeable: yes |
| | InSolution MG-132 in EtOH, ≥95% by HPLC - Calbiochem Preparation Products And Raw materials |
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