| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:DK-AH 269
CAS:186097-54-1
Purity:>=98% (HPLC) Package:5mg, 25mg Remarks:D6942
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| | DK-AH 269 Basic information |
| Product Name: | DK-AH 269 | | Synonyms: | Cilobradine (hydrochloride);Cilobradine hydrochloride, (S)-(+)-7,8-Dimethoxy-3-[[1-(2-(3,4-dimethoxyphenyl)ethyl)-3-piperidinyl]methyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride;Cilobradine DK-AH;(S)-(+)-7,8-Dimethoxy-3-[[1-(2-(3,4-dimethoxyphenyl)ethyl)-3-piperidinyl]methyl]-1,3,4,5-tetrahydro-2H-3-benzazepin-2-one hydrochloride;DK-AH 269 >=98% (HPLC), solid;Cilobradine
(DK-AH 269;DK-AH 269;DKAH-269 | | CAS: | 186097-54-1 | | MF: | C28H38N2O5.ClH | | MW: | 519.078 | | EINECS: | | | Product Categories: | | | Mol File: | 186097-54-1.mol |  |
| | DK-AH 269 Chemical Properties |
| storage temp. | 2-8°C | | solubility | H2O: ~20 mg/mL | | form | solid | | color | white |
| | DK-AH 269 Usage And Synthesis |
| Uses | DK-AH 269 has been used as a hyperpolarization-activated and cyclic nucleotide-gated channel (HCN) antagonist to study its effects on the inhibition of Ih?in?HCN-deficient hair cells of mice. It has also been used as an HCN blocker to study its effects on action potential firing in the suprachiasmatic nucleus (SCN) neurons. | | Biochem/physiol Actions | DK-AH 269 is a bradycardiac agent. |
| | DK-AH 269 Preparation Products And Raw materials |
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