| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
010-82848833 400-666-7788 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:6β-Hydroxy Eplerenone
CAS:209253-80-5
Package:2.5Mg,25Mg
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| | 6-B-HYDROXY EPLERENONE Basic information |
| Product Name: | 6-B-HYDROXY EPLERENONE | | Synonyms: | 6-B-HYDROXY EPLERENONE;6--Hydroxy Eplerenone;(6β,7α,11α,17α)-9,11-Epoxy-6,17-dihydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester;Eplerenone 6-beta-Hydroxy Analog;6-beta-Hydroxy Eplerenone;Eplerenone Impurity 11;Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-6,17-dihydroxy-3-oxo-, γ-lactone, methyl ester, (6β,7α,11α,17α)-;6β-Hydroxy Eplerenone | | CAS: | 209253-80-5 | | MF: | C24H30O7 | | MW: | 430.49 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Steroids | | Mol File: | 209253-80-5.mol |  |
| | 6-B-HYDROXY EPLERENONE Chemical Properties |
| Melting point | 128-135°C | | Boiling point | 642.7±55.0 °C(Predicted) | | density | 1.37±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Methanol (Slightly) | | pka | 13.16±0.70(Predicted) | | form | Solid | | color | White to Off-White |
| | 6-B-HYDROXY EPLERENONE Usage And Synthesis |
| Description | 6β-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone . It is formed from eplerenone by the cytochrome P450 (CYP) isoform CYP3A4. | | Chemical Properties | White to Off-White Solid | | Uses | A metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. | | Uses | 6-B-HYDROXY EPLERENONE is a metabolite of Eplerenone, which is used alone or in combination with other medications to treat high blood pressure. 6-B-HYDROXY EPLERENONE is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure. |
| | 6-B-HYDROXY EPLERENONE Preparation Products And Raw materials |
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